2,4,4'-Trihydroxychalcone

Base Information

Chemical Name:2,4,4'-Trihydroxychalcone
CAS No.:83616-07-3
Molecular Formula:C15H12O4
Molecular Weight:256.258
Hs Code.:2914501900
DSSTox Substance ID:DTXSID301003600
Wikidata:Q82998201,Q105284451
Mol file:83616-07-3.mol

Synonyms:2,4,4'-Trihydroxychalcone;83616-07-3;VDYSHUXENHRSOO-UHFFFAOYSA-N;3-(2,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one;DTXSID301003600;MFCD00049007;SY048111

Suppliers and Price of 2,4,4'-Trihydroxychalcone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,4,4-TRIHYDROXYBENZALACETOPHENONE 95.00%
5MG
$ 496.23

Total 23 raw suppliers

Chemical Property of 2,4,4'-Trihydroxychalcone

Chemical Property:

PSA：77.76000
LogP:2.69950
XLogP3:2.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:256.07355886
Heavy Atom Count:19
Complexity:331

Purity/Quality:

99% ^*data from raw suppliers

2,4,4-TRIHYDROXYBENZALACETOPHENONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)C=CC2=C(C=C(C=C2)O)O)O

Technology Process of 2,4,4'-Trihydroxychalcone

There total 11 articles about 2,4,4'-Trihydroxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 24533-49-1
(E)-3-(2,4-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one

: 83616-07-3
trans-3-(2,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.bmcl.2016.06.033

Reference yield: 60.0%

: 99-93-4
4-Hydroxyacetophenone

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 83616-07-3
(Z)-3-(2,4-dihydroxyphenyl)-1-(4'-hydroxyphenyl)-2-propen-1-one

Guidance literature:: With boron trifluoride diethyl etherate; In 1,4-dioxane; at 20 ℃; for 24h; stereospecific reaction;
DOI:10.1016/j.bmcl.2016.06.033

Reference yield: 20.0%

: 13709-06-3
2,4-bis(methoxymethoxy)benzaldehyde

: 99-93-4
4-Hydroxyacetophenone

: 83616-07-3
trans-3-(2,4-dihydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

Guidance literature:: 2,4-bis(methoxymethoxy)benzaldehyde; 4-Hydroxyacetophenone; With potassium hydroxide; In ethanol; water; at 20 ℃;

With hydrogenchloride; In ethanol; water;
DOI:10.1016/j.ejmech.2014.09.039