1,2-Diphenylpyrrole

Base Information

• Chemical Name: 1,2-Diphenylpyrrole
• CAS No.: 837-56-9
• Molecular Formula: C16H13N
• Molecular Weight: 219.286
• DSSTox Substance ID: DTXSID30395774
• Nikkaji Number: J685.283A
• Wikidata: Q82196050
• Mol file: 837-56-9.mol

Synonyms:1,2-diphenylpyrrole;diphenyl 1h pyrrole;837-56-9;1,2-diphenyl-1H-pyrrole;SCHEMBL347805;DTXSID30395774

Chemical Property of 1,2-Diphenylpyrrole

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 219.104799419
• Heavy Atom Count: 17
• Complexity: 226

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CN2C3=CC=CC=C3

Technology Process of 1,2-Diphenylpyrrole

There total 40 articles about 1,2-Diphenylpyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-phenylimino-1-phenyl-2-butyne (334026-33-4) → 1-phenyl-2-phenylpyrrole (837-56-9)

Guidance literature:

With copper(l) iodide; triethylamine; In N,N-dimethyl acetamide; at 110 ℃; for 4h;

DOI:10.1021/ja0058684

Reference yield: 85.0%

C16H14(2)H2BNO3 → 1-phenyl-2-phenylpyrrole (837-56-9)

Guidance literature:

In [⁽²⁾H₆]acetone; at 20 ℃;

DOI:10.1021/acs.joc.5b00593

Reference yield: 78.0%

1-phenylpyrrole (635-90-5) + chlorobenzene (108-90-7) → 1-phenyl-2-phenylpyrrole (837-56-9)

Guidance literature:

With 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; hexane; pentane; at 40 ℃; for 24h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ja200184b

upstream raw materials:

2-(2'-Chlorophenyl)-1-phenylpyrrole

4-oxo-4-phenyl-butyraldehyde

aniline

benzylidene phenylamine

Downstream raw materials:

2-<<4-(2-methoxyphenyl)-1-piperazinyl>methyl>-1,5-diphenylpyrrole