6-(octylaMino)pyriMidine-2,4(1H,3H)-dione

Base Information

Chemical Name:6-(octylaMino)pyriMidine-2,4(1H,3H)-dione
CAS No.:83797-69-7
Molecular Formula:C₁₂H₂₁N₃O₂
Molecular Weight:239.318
Hs Code.:

Synonyms:GTPL5846;6-Octylaminouracil;

Suppliers and Price of 6-(octylaMino)pyriMidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
GTPL-5846(6-OAU) >98%
100 mg
$ 400.00

DC Chemicals
GTPL-5846(6-OAU) >98%
1 g
$ 1600.00

CSNpharm
6-OAU
50mg
$ 1440.00

CSNpharm
6-OAU
1mg
$ 140.00

Crysdot
6-OAU 98+%
5mg
$ 245.00

Crysdot
6-OAU 98+%
10mg
$ 350.00

Crysdot
6-OAU 98+%
50mg
$ 1050.00

ChemScene
6-OAU 99.94%
50mg
$ 1800.00

ChemScene
6-OAU 99.94%
10mg
$ 600.00

ChemScene
6-OAU 99.94%
5mg
$ 420.00

Total 24 raw suppliers

Chemical Property of 6-(octylaMino)pyriMidine-2,4(1H,3H)-dione

Chemical Property:

PSA：77.75000
LogP:1.90860
Solubility.:≤0.25mg/ml in DMSO;0.25mg/ml in dimethyl formamide

Purity/Quality:

99%, ^*data from raw suppliers

GTPL-5846(6-OAU) >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description GPR84 is a Gαi protein-coupled receptor that is activated by medium-chain free fatty acids, but only at micromolar concentrations. GPR84 is expressed in leukocytes and its expression is further induced by LPS. 6-OAU is a synthetic agonist for GPR84 (EC50 = 512 nM). It has insignificant actions at a panel of 69 other receptors, channels, or transporters. 6-OAU promotes chemotaxis in human neutrophils (EC50 = 318 nM) and amplifies TNF-α production by LPS-treated U937 macrophages. In rats, 6-OAU (1 mg/ml) drives the recruitment of neutrophils and macrophages when injected into a subcutaneous air pouch and raises serum levels of CXCL1 (growth-regulated α protein) when delivered intravenously.

Technology Process of 6-(octylaMino)pyriMidine-2,4(1H,3H)-dione

There total 1 articles about 6-(octylaMino)pyriMidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%