7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one

Base Information

Chemical Name:7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one
CAS No.:83805-64-5
Molecular Formula:C₁₁H₉IO₄
Molecular Weight:332.095
Hs Code.:
DSSTox Substance ID:DTXSID50356160
Wikidata:Q82135373

Synonyms:83805-64-5;7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one;7-hydroxy-8-iodo-5-methoxy-2-methylchromen-4-one;4H-1-Benzopyran-4-one, 7-hydroxy-8-iodo-5-methoxy-2-methyl-;AN-970/40920733;DTXSID50356160

Suppliers and Price of 7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one

Chemical Property:

PSA：59.67000
LogP:2.42020
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:331.95456
Heavy Atom Count:16
Complexity:328

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=O)C2=C(C=C(C(=C2O1)I)O)OC

Technology Process of 7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one

There total 4 articles about 7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 3449-40-9
7-hydroxy-5-methoxy-2-methylchromone

: 83805-64-5
7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-1-benzopyran-4-one

Guidance literature:: With iodine; periodic acid; In ethanol; for 2h; Ambient temperature;
DOI:10.1246/bcsj.55.2649

Reference yield:

: 39548-89-5
1-(4-(benzyloxy)-2-hydroxy-6-methoxyphenyl)ethan-1-one

: 83805-64-5
7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-1-benzopyran-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 52 percent / Na / 3 h / Heating

2: 80 percent / conc. H₂SO₄ / ethanol / 0.5 h / Heating

3: 57 percent / H₂ / 5percent Pd/C / ethyl acetate

4: 89 percent / I₂, periodic acid / ethanol / 2 h / Ambient temperature

With sulfuric acid; hydrogen; iodine; sodium; periodic acid; palladium on activated charcoal; In ethanol; ethyl acetate;
DOI:10.1246/bcsj.55.2649

Reference yield:

: 83805-62-3
7-benzyloxy-5-methoxy-2-methyl-4H-1-benzopyran-4-one

: 83805-64-5
7-hydroxy-8-iodo-5-methoxy-2-methyl-4H-1-benzopyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / H₂ / 5percent Pd/C / ethyl acetate

2: 89 percent / I₂, periodic acid / ethanol / 2 h / Ambient temperature

With hydrogen; iodine; periodic acid; palladium on activated charcoal; In ethanol; ethyl acetate;
DOI:10.1246/bcsj.55.2649