4-Methoxy-3-(methylsulfanyl)quinoline

Base Information

Chemical Name:4-Methoxy-3-(methylsulfanyl)quinoline
CAS No.:83936-11-2
Molecular Formula:C11H11NOS
Molecular Weight:205.28
Hs Code.:
DSSTox Substance ID:DTXSID60574474
Nikkaji Number:J1.206.079C
Wikidata:Q82463521

Synonyms:83936-11-2;4-Methoxy-3-(methylsulfanyl)quinoline;4-methoxy-3-methylthioquinoline;DTXSID60574474

Suppliers and Price of 4-Methoxy-3-(methylsulfanyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 4-Methoxy-3-(methylsulfanyl)quinoline

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.05613515
Heavy Atom Count:14
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=NC2=CC=CC=C21)SC

Technology Process of 4-Methoxy-3-(methylsulfanyl)quinoline

There total 2 articles about 4-Methoxy-3-(methylsulfanyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 100-67-4
potassium phenolate

: 131519-70-5
4-methoxy-3'-methylsulfanyl-3,4'-diquinolinyl sulfide

: 74-88-4
methyl iodide

: 4-phenoxy-3-methylsulfanylquinoline

: 83936-11-2
4-methoxy-3-methylsulfanylquinoline

: 119118-97-7
3-<<3-(methylthio)-4-quinolinyl>thio>-4(1H)-quinolinone

Guidance literature:: potassium phenolate; 4-methoxy-3'-methylsulfanyl-3,4'-diquinolinyl sulfide; In dimethyl sulfoxide; at 70 ℃; for 1.5h;

methyl iodide; In water; dimethyl sulfoxide; at 20 ℃; for 0.5h;

With hydrogenchloride; In water; dimethyl sulfoxide; at 20 ℃;
DOI:10.3987/COM-05-10370

Reference yield:

: 109179-13-7
[3-(3-Methylsulfanyl-quinolin-4-ylsulfanyl)-quinolin-4-yl]-phenyl-acetonitrile

: 74-88-4
methyl iodide

: 83936-11-2
4-methoxy-3-methylsulfanylquinoline

: 109179-16-0
3-methylthio-4-benzoylquinoline

Guidance literature:: With sodium methylate; Yield given. Multistep reaction. Yields of byproduct given;

Reference yield:

: 83936-11-2
4-methoxy-3-methylsulfanylquinoline

: 12-benzyl-9-methylthioquinobenzothiazine

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hexacyanoferrate(III)

2.1: diethylene glycol / 3 h / Reflux

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 20 °C

3.2: 24 h / 20 °C

With sodium hydride; potassium hexacyanoferrate(III); In N,N-dimethyl-formamide; mineral oil; diethylene glycol;
DOI:10.1016/j.molstruc.2016.05.082