(E)-2-Benzylidenecyclohexanone

Base Information

• Chemical Name: (E)-2-Benzylidenecyclohexanone
• CAS No.: 1467-15-8
• Molecular Formula: C₁₃H₁₄O
• Molecular Weight: 186.254
• European Community (EC) Number: 227-144-9
• Nikkaji Number: J352.679H,J39.717B
• Mol file: 1467-15-8.mol

Synonyms:2-Benzylidenecyclohexanone;(E)-2-Benzylidenecyclohexanone;5682-83-7;1467-15-8;2-[(E)-Benzylidene]cyclohexanone;2-BENZYLIDENCYCLOHEXANONE;trans-2-Benzylidenecyclohexanone;(2E)-2-benzylidenecyclohexan-1-one;Cyclohexanone, 2-(phenylmethylene)-, (E)-;2-Benzylidenecyclohexan-1-one;2-(phenylmethylene)cyclohexan-1-one;2-Benzalcyclohexanone;E-2-Benzylidenecyclohexanone;SCHEMBL10734311;(2E)-2-Benzylidenecyclohexanone;(E)-2-(benzylidene)cyclohexanone;(2E)-2-Benzylidenecyclohexanone #;MFCD00070483;STL301748;(2E)-2-benzylidene-cyclohexan-1-one;AKOS002300807;Cyclohexanone, 2-benzylidene-, (E)-;AS-44231;PS-11339;A8123;B0385

Chemical Property of (E)-2-Benzylidenecyclohexanone

Chemical Property:

• Boiling Point: 330.2°Cat760mmHg
• Flash Point: 136°C
• PSA: 0.00000
• Density: 1.09g/cm³
• LogP: 0.00000
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 186.104465066
• Heavy Atom Count: 14
• Complexity: 234

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(=O)C(=CC2=CC=CC=C2)C1
• Isomeric SMILES: C1CCC(=O)/C(=C/C2=CC=CC=C2)/C1

Technology Process of (E)-2-Benzylidenecyclohexanone

There total 47 articles about (E)-2-Benzylidenecyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + benzaldehyde (100-52-7) → (E)-2-benzylidenecyclohexanone (5682-83-7,31021-02-0,1467-15-8)

Guidance literature:

With propylamine; Bi(S(CH₂C₆H₄)2)(H₂O)⁽¹⁺⁾*BF₄^(1-)=[Bi(H₂O)(S(CH₂C₆H₄)2)]BF₄; at 20 ℃; for 6h; diastereoselective reaction; Ionic liquid;

DOI:10.1039/c004940a

Reference yield: 92.0%

2-(hydroxyphenylmethyl)cyclohexan-1-one (13161-18-7,42052-56-2,66607-57-6,66607-58-7,56072-25-4) → (E)-2-benzylidenecyclohexanone (5682-83-7,31021-02-0,1467-15-8)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 0.5h; Heating; Dean-Stark tube;

DOI:10.1016/0040-4039(95)01999-X

Reference yield: 90.0%

2-bromocyclohexanone (1056477-06-5,822-85-5) + benzaldehyde (100-52-7) → (E)-2-benzylidenecyclohexanone (5682-83-7,31021-02-0,1467-15-8)

Guidance literature:

With cerium(III) triiodide; In tetrahydrofuran; for 1h; Ambient temperature;

upstream raw materials:

2-(hydroxyphenylmethyl)cyclohexan-1-one

cyclohexanone

benzaldehyde

2-(hydroxymethylene)cyclohexanone

Downstream raw materials:

2-(α-piperidinobenzyl)cyclohexanon

2-(α-Morpholino-benzyl)-cyclohexanol

2-[α-(4-methyl-piperazino)-benzyl]-cyclohexanone

(+/-)(1Ξ)-trans-2-[(Ξ)-α-(4-ethyl-piperazino)-benzyl]-cyclohexanol