6-quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-1,4-dim

Base Information

• Chemical Name: 6-quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-1,4-dim
• CAS No.: 841275-84-1
• Molecular Formula: C10H9ClN2O4S
• Molecular Weight: 288.70700
• Mol file: 841275-84-1.mol

Synonyms:1,4-Dimethyl-2,3-dioxo-1,2,3,4-tetrahydro-quinoxaline-6-sulfonyl chloride;

Chemical Property of 6-quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-1,4-dim

Chemical Property:

• Melting Point: 250 - 252 °C (petroleum ether)
• PSA: 86.52000
• LogP: 1.24550

Purity/Quality:

97% ^*data from raw suppliers

1,4-Dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-1,4-dim

There total 1 articles about 6-quinoxalinesulfonyl chloride, 1,2,3,4-tetrahydro-1,4-dim which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1,4-dimethylquinoxaline-2,3(1H,4H)-dione (58175-07-8) → 1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride (841275-84-1)

Guidance literature:

With chlorosulfonic acid; at 65 - 90 ℃; for 3h;

DOI:10.1055/s-2004-834888

Reference yield: 85.0%

sulphapyridine (144-83-2) + 1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride (841275-84-1) → 1,4-dimethyl-2,3-dioxo-N-(4-(N-pyridin-2-ylsulfamoyl)phenyl)-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

Guidance literature:

With triethylamine; In ethanol; for 6h; Reflux;

DOI:10.1039/d1ra06799k

Reference yield: 83.0%

Sulfathiazole (72-14-0) + 1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonyl chloride (841275-84-1) → 1,4-dimethyl-2,3-dioxo-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

Guidance literature:

With triethylamine; In ethanol; for 6h; Reflux;

DOI:10.1039/d1ra06799k

upstream raw materials:

1,4-dimethylquinoxaline-2,3(1H,4H)-dione