Phthalate

Base Information

Chemical Name:Phthalate
CAS No.:3198-29-6
Molecular Formula:C8H4 O4
Molecular Weight:164.117
Hs Code.:
DSSTox Substance ID:DTXSID10185812
Nikkaji Number:J269.453K
Wikidata:Q27102460
NCI Thesaurus Code:C152072

Synonyms:disodium phthalate;phthalate;phthalic acid;phthalic acid, copper salt;phthalic acid, dipotassium salt;phthalic acid, disodium salt;phthalic acid, monobarium salt;phthalic acid, monocalcium salt;phthalic acid, monoiron (2+) salt;phthalic acid, monolead (2+) salt;phthalic acid, monopotassium salt;phthalic acid, monoruthenium salt;phthalic acid, monosodium salt;phthalic acid, potassium salt;phthalic acid, potassium, sodium salt;phthalic acid, sodium salt;potassium hydrogen phthalate

Suppliers and Price of Phthalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phthalate

Chemical Property:

Boiling Point:378.3°Cat760mmHg
Flash Point:196.7°C
PSA：80.26000
Density:g/cm³
LogP:-1.58640
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.01095860
Heavy Atom Count:12
Complexity:166

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)[O-])C(=O)[O-]
Description Phthalate esters are a main group of plasticizers, including di-(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP) as the most widely used phthalates, which can be the subject of argument regarding their probable side effects on children’s health. Additionally, these compounds are mainly used as the constituents of many commercial products such as cosmetics, paper coating, paints, and adhesives. In various industries, different O-phthalic acid esters and also other isomers have been widely used. The ortho esters of phthalic acid were identified in seawater and rivers in 1975. Finding these compounds in water and also in marine animals revealed that they reached to the seas in an uncontrolled way. Alongside the other isomer of phthalic acid dimethyl ester, dimethyl terephthalate (DMT) has been isolated and identified as pollutants in a numerous red algae: Phyllophora neruosa, Acanthophora delilei, and Hypnea musciformis. Interestingly, a report on 14C content analysis and isolation of dibutyl phthalate (DBP) from two brown algae (Undaria pinnatifida and Laminaria japonica) and a green alga (Ulva sp.) raised a concern that DBP might be generated naturally.Phthalates have been of great concern because of being either ubiquitous environmental pollution and contaminants or toxic to phyto- and zooplanktons, fish, and arthropods. Phthalic acid esters are documented to accumulate irreversibly in organisms, of which DBP has been reported to exhibit not only carcinogenesis in diverse aquatic animals and hydrophytes but also adverse effects on male reproductive systems, leading to threats to the freshwater ecosystem.
Uses Phthalates are widely employed in many personal care products, cosmetics as well as plastics (softening of products made by these materials, especially vinyl plastics), paper coating, paints, and adhesives. Although The Campaign for Safe Cosmetics revealed the presence of phthalates only in nail polish as an ingredient, phthalates may be detected in many evaluated products, even in products that have not included phthalate in their labels. Shampoo, body deodorant, body wash, hairspray, and hair gels are examples. Although the levels of phthalates in bottled waters have been detected as low, high consumption of such waters leads to a concern. It is recommended to take special care regarding the storage conditions on bottles. Surprisingly, enteric-coated pharmaceutical tablets and nutritional supplements to viscosity control agents also contain phthalates.DEHP is generally applied in medical devices, including cardiac catheters, endotracheal tubes, and some implanted devices, whereas DINP is commonly found in wires, cables, hoses, and plastic toys. Unfortunately, plastic containers, such as food utilities, are the main source of DEHP, in which phthalates are physically dissolved in plastic not by chemical bounding. It is claimed that phthalates are never employed in plastic food wraps marketing in the United States. According to literature from the Pediatric Environmental Health Specialty Units program, some advice should be kept in mind to avoid releasing of phthalate from plastic containers: food/beverages and plastic clean wraps should not be heated at microwave in plastic containers and also plastics should not be placed in the dishwasher. Safe alternatives such as glass or polyethylene plastics and phthalate-free labeled are highly recommended.

Technology Process of Phthalate

There total 6 articles about Phthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-trichlorobenzoate anion

: 67-66-3,8013-54-5
chloroform

: 3198-29-6
o-phthalate

Guidance literature:: With water; hydroxide; In 1,4-dioxane; at 30 ℃; Rate constant; Thermodynamic data; ΔH(excit.), ΔS(excit.);
DOI:10.1039/a807438k

Reference yield:

: 2-tribromobenzoate anion

: 75-25-2
Bromoform

: 3198-29-6
o-phthalate

Guidance literature:: With water; hydroxide; In 1,4-dioxane; at 30 ℃; Rate constant; Thermodynamic data; ΔH(excit.), ΔS(excit.);
DOI:10.1039/a807438k