Salazosulfadimidine

Base Information

• Chemical Name: Salazosulfadimidine
• CAS No.: 2315-08-4
• Molecular Formula: C19H17 N5 O5 S
• Molecular Weight: 427.44
• European Community (EC) Number: 219-016-6
• UNII: W33009B02O
• DSSTox Substance ID: DTXSID101018136,DTXSID80862901
• Nikkaji Number: J7.395D
• Wikidata: Q27292237
• NCI Thesaurus Code: C72843
• ChEMBL ID: CHEMBL2107040
• Mol file: 2315-08-4.mol

Synonyms:Salazosulfadimidine;Salazosulphadimidine;2315-08-4;azudimidine;salazodimidine;salcylazosulfamethazine;salicylazosulfadimidine;W33009B02O;Salazosulfadimidina;Salazosulfadimidinum;Salazo-sulfadimidinum;Salazosulfadimidine [INN];SCHEMBL150333;Salazosulfadimidine [INN:BAN];SCHEMBL1982566;SALAZOSULFADIMIDINE [MI];CHEMBL2107040;UNII-W33009B02O;DTXSID80862901;Salazosulfadimidinum [INN-Latin];CHEBI:135693;Salazosulfadimidina [INN-Spanish];DTXSID101018136;EINECS 219-016-6;Q27292237;5-(p-((4,6-Dimethyl-2-pyrimidinyl)sulfamoyl)phenylazo)salicylic acid;3-(2-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}hydrazinylidene)-6-oxocyclohexa-1,4-diene-1-carboxylic acid

Chemical Property of Salazosulfadimidine

Chemical Property:

• Vapor Pressure: 4.29E-19mmHg at 25°C
• Melting Point: 207°
• Boiling Point: 674.1°Cat760mmHg
• Flash Point: 361.5°C
• PSA: 162.58000
• Density: 1.49g/cm³
• LogP: 4.86720
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 6
• Exact Mass: 427.09503983
• Heavy Atom Count: 30
• Complexity: 709

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O)C

Technology Process of Salazosulfadimidine

There total 2 articles about Salazosulfadimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulfadimesine (57-68-1) + aspirin (50-78-2,98201-60-6) → 5-[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenylazo]-2-hydroxy-benzoic acid (2315-08-4)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water;

Reference yield:

salicylic acid (69-72-7,25496-36-0,8052-31-1) → 5-[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenylazo]-2-hydroxy-benzoic acid (2315-08-4)

Guidance literature:

upstream raw materials:

salicylic acid

sulfadimesine

aspirin

Refernces