1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-

Base Information

• Chemical Name: 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-
• CAS No.: 22713-97-9
• Molecular Formula: C14H12 N4 S
• Molecular Weight: 268.342
• Mol file: 22713-97-9.mol

Synonyms:1,2,4-Thiadiazole,3,5-dianilino- (6CI,7CI,8CI); 1,2,4-Thiadiazole-3,5-diamine, N,N'-diphenyl-(9CI); 3,5-Dianilino-1,2,4-thiadiazole; Dost's base

Chemical Property of 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-

There total 10 articles about 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-phenyl-N'-phenylcarbamimidoyl-thiourea (22713-99-1) → N3,N5-diphenyl-1,2,4-thiadiazole-3,5-diamine (22713-97-9)

Guidance literature:

With iodine; potassium carbonate; In acetonitrile; at 20 ℃; for 0.25h;

DOI:10.1021/acs.joc.7b00814

Reference yield: 55.0%

monophenylthiourea (103-85-5) → N3,N5-diphenyl-1,2,4-thiadiazole-3,5-diamine (22713-97-9)

Guidance literature:

With [bis(acetoxy)iodo]benzene; In acetonitrile; at 20 ℃; for 0.5h;

DOI:10.1016/S0040-4020(03)01176-1

Reference yield:

→ N3,N5-diphenyl-1,2,4-thiadiazole-3,5-diamine (22713-97-9)

Guidance literature:

With ammonia; at 140 ℃;

DOI:10.1039/jr9630003333

upstream raw materials:

N-phenyl-N'-phenylcarbamimidoyl-thiourea

5-imino-4-phenyl-3-phenylamino-4,5-dihydro-1,2,4-thiadiazoline

p-toluidine

aniline

Downstream raw materials:

3,5-bis(N-methylphenylamino)-1,2,4-thiadiazole