N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide

Base Information

Chemical Name:N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide
CAS No.:133025-23-7
Molecular Formula:C₂₄H₃₃N₃O₂
Molecular Weight:395.545
Hs Code.:
European Community (EC) Number:683-580-3
DSSTox Substance ID:DTXSID80927903
Nikkaji Number:J546.216I
Wikipedia:WAY-100135
Wikidata:Q7946878
Pharos Ligand ID:43YFVGGDJJ2F
ChEMBL ID:CHEMBL22564
Mol file:133025-23-7.mol

Synonyms:N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide;WAY 100135;WAY-100135

Suppliers and Price of N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
(S)-WAY100135dihydrochloride ≥99%(HPLC)
10
$ 169.00

Tocris
(S)-WAY100135dihydrochloride ≥99%(HPLC)
50
$ 710.00

Sigma-Aldrich
WAY-100135 ≥98% (HPLC)
25 mg
$ 458.00

Sigma-Aldrich
WAY-100135 ≥98% (HPLC)
5 mg
$ 118.00

Total 11 raw suppliers

Chemical Property of N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide

Chemical Property:

Vapor Pressure:1.43E-13mmHg at 25°C
Boiling Point:582.8°Cat760mmHg
Flash Point:306.3°C
PSA：44.81000
Density:1.085g/cm³
LogP:5.51350
Storage Temp.:Desiccate at +4°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:395.25727730
Heavy Atom Count:29
Complexity:505

Purity/Quality:

98%min ^*data from raw suppliers

(S)-WAY100135dihydrochloride ≥99%(HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NC(=O)C(CN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3
Uses (S)-WAY 100135 Dihydrochloride is a selective 5-?HT1A receptor antagonist.

Technology Process of N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide

There total 3 articles about N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 133025-23-7
N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: propan-2-ol / Heating

2: 1,1'-carbonyldiimidazoloe (CDI) / CH₂Cl₂

With 1,1'-carbonyldiimidazole; In dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00062a028

Reference yield:

: 492-38-6
2-phenylacrylic acid

: 133025-23-7
N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: propan-2-ol / Heating

2: 1,1'-carbonyldiimidazoloe (CDI) / CH₂Cl₂

With 1,1'-carbonyldiimidazole; In dichloromethane; isopropyl alcohol;
DOI:10.1021/jm00062a028