3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester

Base Information

Chemical Name:3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester
CAS No.:845744-10-7
Molecular Formula:C25H33ClN4O4
Molecular Weight:489.014
Hs Code.:

3-Pyridinecarboxylic acid,
4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-
2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester

Synonyms:

Suppliers and Price of 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester

There total 2 articles about 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-2-[[[2-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-methylpropyl]amino]methyl]-1,4-dihydro-6-methyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 320581-09-7
(2-amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester

: 845744-09-4
methyl 2-(bromomethyl)-4-(2-chlorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate

: 845744-10-7
methyl 2-[({2-[(tert-butoxy)carbonylamino]-2-methylpropyl}amino)methyl]-4-(2-chlorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate

Guidance literature:: In DMF (N,N-dimethyl-formamide); at 50 ℃; for 3h;

Reference yield:

: 67593-29-7
methyl 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-2,6-dimethylpyridine-3-carboxylate

: 845744-10-7
methyl 2-[({2-[(tert-butoxy)carbonylamino]-2-methylpropyl}amino)methyl]-4-(2-chlorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridinium hydrobromide perbromide

2: DMF (N,N-dimethyl-formamide) / 3 h / 50 °C

With pyridinium hydrobromide perbromide; In DMF (N,N-dimethyl-formamide);