Cryptolepine

Base Information

Chemical Name:Cryptolepine
CAS No.:480-26-2
Molecular Formula:C16H12N2
Molecular Weight:232.2799
Hs Code.:
UNII:OF1UIT4RDH
DSSTox Substance ID:DTXSID6037645
Nikkaji Number:J13.757J
Wikipedia:Cryptolepine
Wikidata:Q5190964
Metabolomics Workbench ID:67950
ChEMBL ID:CHEMBL119096
Mol file:480-26-2.mol

Synonyms:10H-Indolo(3,2-b)quinoline;5-methylquinolo(2',3'-3,2)indole;cryptolepine;cryptolepine monohydrochloride

Suppliers and Price of Cryptolepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Cryptolepine hydrate ≥98% (HPLC)
10mg
$ 214.00

Sigma-Aldrich
Cryptolepine hydrate ≥98% (HPLC)
50mg
$ 888.00

American Custom Chemicals Corporation
CRYPTOLEPINE 95.00%
5MG
$ 497.32

Total 10 raw suppliers

Chemical Property of Cryptolepine

Chemical Property:

Vapor Pressure:6.42E-07mmHg at 25°C
Melting Point:173-175 °C
Boiling Point:409.6°Cat760mmHg
PKA:11.19±0.20(Predicted)
Flash Point:201.5°C
PSA：17.82000
Density:1.21g/cm³
LogP:3.87970
Storage Temp.:2-8°C
Solubility.:DMSO: ≥5mg/mL
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:232.100048391
Heavy Atom Count:18
Complexity:316

Purity/Quality:

99% ^*data from raw suppliers

Cryptolepine hydrate ≥98% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-37/38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C=C3C1=C4C=CC=CC4=N3

Technology Process of Cryptolepine

There total 23 articles about Cryptolepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 5-methyl-10H-indolo[3,2-b]quinolin-5-ium trifluoromethane sulfonate

: 480-26-2
cryptolepine

Guidance literature:: With sodium carbonate; In water; for 0.25h;
DOI:10.1021/jm0010419

Reference yield: 71.0%

: 243-58-3
quindoline

: 74-88-4
methyl iodide

: 480-26-2
cryptolepine

Guidance literature:: With potassium hydroxide; barium(II) oxide; In acetone; for 4h; Heating;
DOI:10.1016/j.tetlet.2005.11.007

Reference yield: 62.0%

: 2-formyl-3-{methyl(phenyl)amino}-1-tosylindole

: 480-26-2
cryptolepine

Guidance literature:: 2-formyl-3-{methyl(phenyl)amino}-1-tosylindole; With N,N-dimethylammonium chloride; In N,N-dimethyl-formamide; at 150 ℃; for 1.5h;

With sodium carbonate; In water; N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;
DOI:10.1021/acs.orglett.7b01940