(S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid

Base Information

Chemical Name:(S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid
CAS No.:847358-98-9
Molecular Formula:C14H16BrF4NO2
Molecular Weight:386.184
Hs Code.:2922499990
Mol file:847358-98-9.mol

Synonyms:(2S)-2-[{(1S)-2,2,2-trifluoro-1-(4-bromophenyl)ethyl}amino]-4-fluoro-4-methylpentanoic acid;N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-L-leucine;(S)-2-(((S)-1-(4-BROMOPHENYL)-2,2,2-TRIFLUOROETHYL)AMINO)-4-FLUORO-4-METHYLPENTANOIC ACID;N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-1-L-leucine;

Suppliers and Price of (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-(((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoicacid 97%
1g
$ 1286.00

ChemScene
(S)-2-((S)-1-(4-bromophenyl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanoicacid
100mg
$ 1320.00

Alichem
(S)-2-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanoicacid
1g
$ 1405.95

Alichem
(S)-2-((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanoicacid
250mg
$ 589.68

Total 5 raw suppliers

Chemical Property of (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid

Chemical Property:

PSA：49.33000
LogP:4.62440

Purity/Quality:

≥95% ^*data from raw suppliers

(S)-2-(((S)-1-(4-Bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid

There total 2 articles about (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 603142-95-6
(2S)-2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-fluoro-4-methylpentan-1-ol

: 847358-98-9
N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-L-leucine

Guidance literature:: With chromium(VI) oxide; periodic acid; In acetonitrile; at 0 - 5 ℃; for 3.5h;

Reference yield:

: C₁₄H₁₃BrF₄NO₂^(1-)*K⁽¹⁺⁾

: 847358-98-9
N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-L-leucine

Guidance literature:: C₁₄H₁₃BrF₄NO₂^(1-)*K⁽¹⁺⁾; With zinc(II) tetrahydroborate; In acetonitrile; at -40 ℃;

With hydrogenchloride; In water; stereoselective reaction;
DOI:10.1016/j.bmcl.2010.10.015

Reference yield:

: 847358-98-9
N-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-L-leucine

: 443918-99-8
(4S,5R)-4-amino-5-methyldihydrofuran-3-(2H)-one hydrochloride

: 847361-73-3
N²-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-N¹-[(2R,3S)-2-methyl-4-oxotetrahydrofuran-3-yl]-L-leucinamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 3h;