2-Methylbutanoic anhydride

Base Information

• Chemical Name: 2-Methylbutanoic anhydride
• CAS No.: 1519-23-9
• Molecular Formula: C10H18 O3
• Molecular Weight: 186.251
• Hs Code.: 2915900090
• European Community (EC) Number: 216-181-6
• DSSTox Substance ID: DTXSID70934363
• Nikkaji Number: J206.730G
• Mol file: 1519-23-9.mol

Synonyms:2-Methylbutanoic anhydride;1519-23-9;2-methylbutanoyl 2-methylbutanoate;2-Methylbutyric anhydride;Butanoic acid, 2-methyl-, anhydride;2-METHYLBUTANOICANHYDRIDE;EINECS 216-181-6;Butanoic acid, 2-methyl-, 1,1'-anhydride;Bis(2-methylbutyric)anhydride;SCHEMBL248665;DTXSID70934363;AKOS006228270;FS-4752;CS-0337113;FT-0773344

Chemical Property of 2-Methylbutanoic anhydride

Chemical Property:

• Vapor Pressure: 0.0129mmHg at 25°C
• Boiling Point: 259.5°Cat760mmHg
• Flash Point: 90°C
• PSA: 43.37000
• Density: 0.955g/cm³
• LogP: 2.14840
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 186.125594432
• Heavy Atom Count: 13
• Complexity: 167

Purity/Quality:

98%min ^*data from raw suppliers

2-Methylbutanoicanhydride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C(=O)OC(=O)C(C)CC

Technology Process of 2-Methylbutanoic anhydride

There total 4 articles about 2-Methylbutanoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Methylbutanoic acid (116-53-0,600-07-7) → 2-methylbutanoic anhydride (1519-23-9)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 4 ℃; for 1h;

DOI:10.1021/jm00349a005

Reference yield:

→ 2-methylbutanoic anhydride (1519-23-9)

Guidance literature:

Reference yield:

2-Methylbutanoic acid (116-53-0,600-07-7) + acetyl chloride (75-36-5) → 2-methylbutanoic anhydride (1519-23-9)

Guidance literature:

upstream raw materials:

2-Methylbutanoic acid

acetyl chloride

Downstream raw materials:

2-Methyl-N-[3-(2-methyl-butyrylamino)-phenyl]-butyramide

2-methyl-1-phenyl-butan-1-one

ethyl 1-<(2'-cyanobiphenyl-4-yl)methyl>-2-(2-methylpropyl)-1H-benzimidazole-7-carboxylate

2-Methyl-N-[3-(2,2,2-trifluoro-acetylamino)-phenyl]-butyramide