4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one

Base Information

Chemical Name:4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
CAS No.:84755-40-8
Molecular Formula:C12H14O4
Molecular Weight:222.241
Hs Code.:
DSSTox Substance ID:DTXSID30553377

Synonyms:4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one;84755-40-8;DTXSID30553377

Suppliers and Price of 4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:222.08920892
Heavy Atom Count:16
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CC2CC(=O)OC2)O

Technology Process of 4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one

There total 5 articles about 4-[(4-Hydroxy-3-methoxyphenyl)methyl]oxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.6%

: 92831-72-6
(benzyloxy-4 methoxy-3 benzylidene)-4 dihydro-3H-furannone-2

: 84755-40-8
(hydroxy-4 methoxy-3 benzyl)-4 dihydro-3H-furannone-2

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 7h; under 3750.3 Torr; Ambient temperature;

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 84755-40-8
(hydroxy-4 methoxy-3 benzyl)-4 dihydro-3H-furannone-2

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / methylate de sodium / 7 h / Heating

2: 66.5 percent / chlorure de calcium, borohydrure de sodium / ethanol; aq. KOH / 1.) room temperature, 5 h; 2.) 0 deg C, pH=1 (HCl 6N); 3.) -20 deg C

3: 77.6 percent / H₂ / Pd/C (10percent) / ethyl acetate / 7 h / 3750.3 Torr / Ambient temperature

With sodium tetrahydroborate; chlorure de calcium; hydrogen; sodium methylate; palladium on activated charcoal; In potassium hydroxide; ethanol; ethyl acetate;

Reference yield:

: 84755-39-5
acide (benzyloxy-4 methoxy-3 phenyl)-4 methoxycarbonyl-3 butene-3 oique

: 84755-40-8
(hydroxy-4 methoxy-3 benzyl)-4 dihydro-3H-furannone-2

Guidance literature:: Multi-step reaction with 2 steps

1: 66.5 percent / chlorure de calcium, borohydrure de sodium / ethanol; aq. KOH / 1.) room temperature, 5 h; 2.) 0 deg C, pH=1 (HCl 6N); 3.) -20 deg C

2: 77.6 percent / H₂ / Pd/C (10percent) / ethyl acetate / 7 h / 3750.3 Torr / Ambient temperature

With sodium tetrahydroborate; chlorure de calcium; hydrogen; palladium on activated charcoal; In potassium hydroxide; ethanol; ethyl acetate;