(1-Propyl-1H-pyrazol-4-yl)boronic acid

Base Information

• Chemical Name: (1-Propyl-1H-pyrazol-4-yl)boronic acid
• CAS No.: 847818-57-9
• Molecular Formula: C6H11BN2O2
• Molecular Weight: 153.977
• Hs Code.: 2933199090
• DSSTox Substance ID: DTXSID30461529
• Mol file: 847818-57-9.mol

Synonyms:(1-Propyl-1H-pyrazol-4-yl)boronic acid;847818-57-9;1-Propylpyrazole-4-boronic acid;1-propyl-1H-pyrazol-4-ylboronic acid;(1-propylpyrazol-4-yl)boronic Acid;SCHEMBL671710;1-propylpyrazol-4-boronic acid;DTXSID30461529;WRPVRKKWSXLHKX-UHFFFAOYSA-N;MFCD11504862;1-propyl-1H-pyrazole-4-boronic acid;AKOS010942749;AB91948;AM85925;(1-Propyl-1H-pyrazol-4-yl)boronicacid;AC-27321;DS-18065;CS-0044697;EN300-212567;A863992

Chemical Property of (1-Propyl-1H-pyrazol-4-yl)boronic acid

Chemical Property:

• PSA: 58.28000
• LogP: -1.02710
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 154.0913578
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

97% ^*data from raw suppliers

1-Propylpyrazole-4-boronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: B(C1=CN(N=C1)CCC)(O)O

Technology Process of (1-Propyl-1H-pyrazol-4-yl)boronic acid

There total 2 articles about (1-Propyl-1H-pyrazol-4-yl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

4-bromo-1-propyl-1H-pyrazole (141302-33-2) → (1-propyl-1H-pyrazol-4-yl)boronic acid (847818-57-9)

Guidance literature:

4-bromo-1-propyl-1H-pyrazole; With n-butyllithium; In tetrahydrofuran; hexane; at -90 ℃; for 1h;

With Trimethyl borate; In tetrahydrofuran; hexane; at -70 ℃; for 0.5h;

With ammonium chloride; In tetrahydrofuran; hexane; at 20 ℃; for 1h;

DOI:10.1002/jhet.5570410612

Reference yield: 30.0%

Triisopropyl borate (5419-55-6) + 4-bromo-1-propyl-1H-pyrazole (141302-33-2) → (1-propyl-1H-pyrazol-4-yl)boronic acid (847818-57-9)

Guidance literature:

4-bromo-1-propyl-1H-pyrazole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

Triisopropyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 3h;

Reference yield: 97.0%

p-(iodophenyl)carboxaldehyde (15164-44-0) + (1-propyl-1H-pyrazol-4-yl)boronic acid (847818-57-9) → 4-(1-propyl-1H-pyrazol-4-yl)benzaldehyde

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; N,N-dimethyl-formamide; at 110 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.9b01526

upstream raw materials:

4-bromo-1-propyl-1H-pyrazole

Triisopropyl borate

Downstream raw materials:

1-propyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

2,2,2-trifluoro-N-(4-fluoro-3-{1-[1-(2-methoxy-ethyl)-4-(1-propyl-1H-pyrazol-4-yl)-1H-indole-3-carbonyl]-piperidin-4-yl}-benzyl)-acetamide

[4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-[1-(2-methoxy-ethyl)-4-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-yl]-methanone hydrochloride

C₂₀H₂₀N₆O₃S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 847818-57-9 1-PROPYL-1H-PYRAZOL-4-YLBORONIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send