1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-

Base Information

Chemical Name:1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-
CAS No.:86523-79-7
Molecular Formula:C19H24 N6 O2
Molecular Weight:368.439
Hs Code.:
DSSTox Substance ID:DTXSID20235630
Wikidata:Q83117510
ChEMBL ID:CHEMBL57030
Mol file:86523-79-7.mol

Synonyms:BRN 5648444;86523-79-7;1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-;N-(4-((Aminocarbonyl)amino)phenyl)-3-(4-(2-pyridinyl)-1-piperazinyl)propanamide;CHEMBL57030;DTXSID20235630;C19H24N6O2;1-Piperazinepropanamide,N-[4-[(aminocarbonyl)amino]phenyl]-4-(2-pyridinyl)-;C19-H24-N6-O2;LS-113157

Suppliers and Price of 1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-PIPERAZINEPROPANAMIDE, N-(4-((AMINOCARBONYL)AMINO)PHENYL)-4-(2-PYRID INYL)- 95.00%
5MG
$ 501.30

Total 3 raw suppliers

Chemical Property of 1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-

Chemical Property:

Vapor Pressure:6.69E-16mmHg at 25°C
Melting Point:207-208 °C(Solv: methanol (67-56-1))
Boiling Point:632.4°Cat760mmHg
PKA:14.42±0.70(Predicted)
Flash Point:336.3°C
PSA：104.58000
Density:1.309g/cm³
LogP:2.38570
XLogP3:0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:368.19607403
Heavy Atom Count:27
Complexity:487

Purity/Quality:: 1-PIPERAZINEPROPANAMIDE, N-(4-((AMINOCARBONYL)AMINO)PHENYL)-4-(2-PYRID INYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(=O)NC2=CC=C(C=C2)NC(=O)N)C3=CC=CC=N3

Technology Process of 1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)-

There total 5 articles about 1-Piperazinepropanamide, N-(4-((aminocarbonyl)amino)phenyl)-4-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: potassium cyanate

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

: 86523-79-7
N-<4-<(aminocarbonyl)amino>phenyl>-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

: 104374-00-7
N-<4-<<<(aminocarbonyl)amino>carbonyl>amino>phenyl>-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: With hydrogenchloride; for 8h;
DOI:10.1021/jm00384a002

Reference yield: 3.0%

: potassium cyanate

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

: 4755-77-5
Ethyl oxalyl chloride

: 86523-79-7
N-<4-<(aminocarbonyl)amino>phenyl>-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: With hydrogenchloride; for 8h;
DOI:10.1021/jm00384a002

Reference yield:

: 34803-66-2
1-(2-pyridyl)piperazine

: 86523-79-7
N-<4-<(aminocarbonyl)amino>phenyl>-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / benzene / Heating

2: 73 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

3: 16 percent / 1 N aq. HCl / 8 h

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; benzene;
DOI:10.1021/jm00384a002