1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol

Base Information

Chemical Name:1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol
CAS No.:76142-63-7
Molecular Formula:C₁₁H₁₉NO₂S
Molecular Weight:229.343
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90997495
Nikkaji Number:J69.766D
Mol file:76142-63-7.mol

Synonyms:BRN 4990366;1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol;76142-63-7;2-Propanol, 1-(tert-butylamino)-3-(3-thienyloxy)-;2-Propanol, 1-((1,1-dimethylethyl)amino)-3-(3-thienyloxy)-;DTXSID90997495;LS-121858;1-(tert-Butylamino)-3-[(thiophen-3-yl)oxy]propan-2-ol

Suppliers and Price of 1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(TERTBUTYLAMINO)-3-(3-THIENYLOXY)-2-PROPANOL 95.00%
5MG
$ 503.10

Total 3 raw suppliers

Chemical Property of 1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol

Chemical Property:

Vapor Pressure:1.12E-05mmHg at 25°C
Boiling Point:355.8°C at 760 mmHg
Flash Point:169°C
PSA：69.73000
Density:1.098g/cm³
LogP:2.26680
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:229.11365002
Heavy Atom Count:15
Complexity:182

Purity/Quality:

99% ^*data from raw suppliers

1-(TERTBUTYLAMINO)-3-(3-THIENYLOXY)-2-PROPANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NCC(COC1=CSC=C1)O

Technology Process of 1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol

There total 4 articles about 1-(tert-Butylamino)-3-(3-thienyloxy)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 76142-58-0
1-(3-thienyloxy)-2,3-epoxypropane

: 75-64-9
tert-butylamine

: 76142-63-7
1-tert-butylamino-3-(3-thienyloxy)-2-propanol

Guidance literature:: for 72h; Ambient temperature;

Reference yield:

: 76142-56-8
3-(3-thienyloxy)-1,2-propanediol

: 76142-63-7
1-tert-butylamino-3-(3-thienyloxy)-2-propanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1) TsCl, 2) 20percent aq. NaOH / 1) pyridine, r.t., 2) DMSO

2: propan-2-ol / Ambient temperature

With sodium hydroxide; p-toluenesulfonyl chloride; In isopropyl alcohol;
DOI:10.1002/ardp.19963290408

Reference yield:

: 177974-47-9
3-(2,3-dihydroxy)propoxythiophene-2-carboxylic acid

: 76142-63-7
1-tert-butylamino-3-(3-thienyloxy)-2-propanol

Guidance literature:: Multi-step reaction with 3 steps

1: 165 °C / 0.1 Torr

2: 1) TsCl, 2) 20percent aq. NaOH / 1) pyridine, r.t., 2) DMSO

3: propan-2-ol / Ambient temperature

With sodium hydroxide; p-toluenesulfonyl chloride; In isopropyl alcohol;
DOI:10.1002/ardp.19963290408