1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid
CAS No.:83-10-3
Molecular Formula:C12H12 N2 O3
Molecular Weight:232.239
Hs Code.:2933199090
European Community (EC) Number:635-123-4
NSC Number:59834
DSSTox Substance ID:DTXSID50289207
Nikkaji Number:J1.429.794D
Wikidata:Q82026408
Mol file:83-10-3.mol

Synonyms:1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid;83-10-3;Antipyric acid;1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carboxylic acid;4-Antipyrinecarboxylic acid;ANTIPYRINECARBOXYLIC ACID;SCHEMBL197736;DTXSID50289207;2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline-4-carboxylic acid;NSC59834;MFCD00020785;NSC-59834;STK950799;1H-Pyrazole-4-carboxylic acid, 2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-;2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-4-carboxylic acid;AKOS002666306;CS-W005600;SB18453;SS-3597;F50515;A901915;2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one-4-carboxylic acid;1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carb oxylic acid;1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid #;1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicacid;1H-Pyrazole-4-carboxylic acid,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-

Suppliers and Price of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicAcid
500mg
$ 110.00

Matrix Scientific
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid 97%
500mg
$ 126.00

Matrix Scientific
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid 97%
1g
$ 159.00

Crysdot
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicacid 95+%
10g
$ 762.00

Crysdot
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicacid 95+%
25g
$ 1525.00

Crysdot
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicacid 95+%
5g
$ 449.00

Chemenu
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicacid 95+%
1g
$ 125.00

Biosynth Carbosynth
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid
2 g
$ 434.00

Biosynth Carbosynth
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid
1 g
$ 255.00

Biosynth Carbosynth
1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid
500 mg
$ 150.00

Total 12 raw suppliers

Chemical Property of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

Chemical Property:

Appearance/Colour:yellow
Vapor Pressure:6.65E-06mmHg at 25°C
Melting Point:213 - 214 °C(methanol); 219 - 221 °C
Boiling Point:363°Cat760mmHg
PKA:6.47±0.20(Predicted)
Flash Point:173.3°C
PSA：64.23000
Density:1.342g/cm³
LogP:1.18260
Storage Temp.:2-8°C
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:383

Purity/Quality:

97% ^*data from raw suppliers

1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)N(N1C)C2=CC=CC=C2)C(=O)O

Technology Process of 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

There total 13 articles about 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 950-81-2
4-formyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one

: 83-10-3
antipyric acid

Guidance literature:: With sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 0 - 20 ℃; for 4h;
DOI:10.1021/jm201330u

Reference yield:

: 6538-52-9
(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-glyoxylic acid

: 83-10-3
antipyric acid

Guidance literature:: With dihydrogen peroxide;
DOI:10.1002/ardp.19562890308

Reference yield:

: 60-80-0
antipyrine

: 83-10-3
antipyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: CS₂; AlCl₃ / anschliessend mit H₂O

2: aqueous H₂O₂

With carbon disulfide; aluminium trichloride; dihydrogen peroxide;
DOI:10.1002/ardp.19562890308