2-(4-Benzoylphenyl)propanoic acid

Base Information

Chemical Name:2-(4-Benzoylphenyl)propanoic acid
CAS No.:22410-97-5
Molecular Formula:C16H14 O3
Molecular Weight:254.285
Hs Code.:
DSSTox Substance ID:DTXSID20945065
Nikkaji Number:J745.061C
Mol file:22410-97-5.mol

Synonyms:2-(4-benzoylphenyl)propanoic acid;p-Benzoylhydratropic acid;22410-97-5;Benzeneacetic acid,4-benzoyl-a-methyl-;4-Benzoyl-alpha-methylbenzeneacetic acid;BRN 2735553;Hydratropic acid, p-benzoyl-;Benzeneacetic acid, 4-benzoyl-alpha-methyl-;SCHEMBL5313395;DTXSID20945065;2-(3-Benzoyl-phenyl)-propionsaure;LS-28620

Suppliers and Price of 2-(4-Benzoylphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(4-Benzoylphenyl)propanoic acid

Chemical Property:

Vapor Pressure:4.09E-08mmHg at 25°C
Boiling Point:428.8°C at 760 mmHg
Flash Point:227.3°C
Density:1.198g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:254.094294304
Heavy Atom Count:19
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)C(=O)C2=CC=CC=C2)C(=O)O

Technology Process of 2-(4-Benzoylphenyl)propanoic acid

There total 8 articles about 2-(4-Benzoylphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 3139-85-3
4-vinylbenzophenone

: 124-38-9,18923-20-1
carbon dioxide

: 22410-97-5
(RS)-2-(4-benzoylphenyl)propanoic acid

Guidance literature:: With chloro(1,5-cyclooctadiene)rhodium(I) dimer; diethylzinc; In N,N-dimethyl-formamide; at 0 ℃; for 3h;
DOI:10.1002/ejoc.201600338

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: C₂₁H₂₅BO₃

: 22410-97-5
(RS)-2-(4-benzoylphenyl)propanoic acid

Guidance literature:: carbon dioxide; C₂₁H₂₅BO₃; With potassium tert-butylate; In tetrahydrofuran; toluene; at -78 ℃; for 3h; under 760.051 Torr;

With hydrogenchloride; In tetrahydrofuran; water; toluene;
DOI:10.1002/chem.201200642

Reference yield:

: 90-90-4
(4-bromophenyl)(phenyl)methanone

: 31469-22-4
1,1-bis(trimethylsilyloxy)prop-1-ene

: 22410-97-5
(RS)-2-(4-benzoylphenyl)propanoic acid

Guidance literature:: (4-bromophenyl)(phenyl)methanone; With zinc(II) fluoride; tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; for 0.666667h; Inert atmosphere;

1,1-bis(trimethylsilyloxy)prop-1-ene; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; at 80 ℃; for 12h; Further stages; Sealed tube; Inert atmosphere;
DOI:10.1021/jacs.9b03291