Zapizolam

Base Information

• Chemical Name: Zapizolam
• CAS No.: 64098-32-4
• Molecular Formula: C15H9 Cl2 N5
• Molecular Weight: 330.176
• Hs Code.: 2933990090
• European Community (EC) Number: 264-670-8
• UNII: MFF90009B9
• DSSTox Substance ID: DTXSID10214292
• Nikkaji Number: J32.857J
• Wikipedia: Zapizolam
• Wikidata: Q8066414
• NCI Thesaurus Code: C66684
• ChEMBL ID: CHEMBL2105523
• Mol file: 64098-32-4.mol

Synonyms:Zapizolam;Zapizolam [INN];Zapizolamum;Zapizolamum [INN-Latin];64098-32-4;EINECS 264-670-8;BRN 1154881;UNII-MFF90009B9;MFF90009B9;D 13129;D-13,129;8-Chloro-6-(2-chlorophenyl)-4H-pyrido(2,3-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine;8-Chloro-6-(o-chlorophenyl)-4H-pyrido(2,3-f)-s-triazolo(4,3-a)(1,4)diazepine;D-13129;4H-Pyrido(2,3-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, 8-chloro-6-(2-chlorophenyl)-;12-chloro-9-(2-chlorophenyl)-2,4,5,8,11-pentazatricyclo[8.4.0.02,6]tetradeca-1(10),3,5,8,11,13-hexaene;C15H9Cl2N5;SCHEMBL2110320;CHEMBL2105523;C15-H9-Cl2-N5;DTXSID10214292;LS-134373;Q8066414;6-(o-chloro-phenyl)-8-chloro-4H-s-triazolo-(4,3-a)-pyrido-(2,3-f)-(1,4)-diazepine

Chemical Property of Zapizolam

Chemical Property:

• Vapor Pressure: 5.49E-12mmHg at 25°C
• Boiling Point: 546.2°C at 760 mmHg
• Flash Point: 284.1°C
• PSA: 55.96000
• Density: 1.58g/cm³
• LogP: 2.75570
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 329.0235007
• Heavy Atom Count: 22
• Complexity: 446

Purity/Quality:

99% ^*data from raw suppliers

ZAPIZOLAM 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C2=NN=CN2C3=C(C(=N1)C4=CC=CC=C4Cl)N=C(C=C3)Cl

Technology Process of Zapizolam

There total 2 articles about Zapizolam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine 5-oxide (64098-30-2) → 8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine (64098-32-4)

Guidance literature:

With anhydrous phosphorus trichloride; In 1,4-dioxane; methanol; chloroform;

Reference yield:

→ 8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine (64098-32-4)

Guidance literature:

entspr.2-Hydrazinobenzdiazepin,Orthoameisensaeuretriaethylester/p-toluolsulfonsaeure;

upstream raw materials:

8-chloro-6-(2-chloro-phenyl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine 5-oxide