Technology Process of 1H-1-Benzazepine, 1-benzoyl-2,3,4,5-tetrahydro-5-methyl-
There total 6 articles about 1H-1-Benzazepine, 1-benzoyl-2,3,4,5-tetrahydro-5-methyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
at 20 ℃;
for 48h;
DOI:10.1021/jo048118b
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 77 percent / NaH / various solvent(s); tetrahydrofuran / 2.5 h / Heating
2: 63 percent / PPh3; LiCl; triethylamine / Pd(OAc)2 / dimethylformamide / 140 °C
3: 86 percent / H2 / Pd/C / methanol / 48 h / 20 °C
With
hydrogen; sodium hydride; triethylamine; triphenylphosphine; lithium chloride;
palladium diacetate; palladium on activated charcoal;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
2: Heck reaction;
DOI:10.1021/jo048118b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 88 percent / PPh3; LiCl; triethylamine / Pd(OAc)2 / dimethylformamide / 22 h / 130 °C
2: 86 percent / H2 / Pd/C / methanol / 48 h / 20 °C
With
hydrogen; triethylamine; triphenylphosphine; lithium chloride;
palladium diacetate; palladium on activated charcoal;
In
methanol; N,N-dimethyl-formamide;
1: Heck reaction;
DOI:10.1021/jo048118b
