2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

Base Information

Chemical Name:2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide
CAS No.:86683-61-6
Molecular Formula:C₁₇H₂₁N₃O₂
Molecular Weight:299.373
Hs Code.:
DSSTox Substance ID:DTXSID001007015

Synonyms:2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide;alpha-Methyl-N-(3-phenyl-5-isoxazolyl)-1-pyrrolidinepropanamide;1-Pyrrolidinepropanamide, alpha-methyl-N-(3-phenyl-5-isoxazolyl)-;86683-61-6;DTXSID001007015;LS-138112;LS-138113;LS-138114;2-Methyl-N-(3-phenyl-1,2-oxazol-5-yl)-3-(pyrrolidin-1-yl)propanamide

Suppliers and Price of 2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

Chemical Property:

Vapor Pressure:1.09E-11mmHg at 25°C
Boiling Point:539.1°Cat760mmHg
Flash Point:279.8°C
Density:1.183g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:299.16337692
Heavy Atom Count:22
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CN1CCCC1)C(=O)NC2=CC(=NO2)C3=CC=CC=C3

Technology Process of 2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

There total 3 articles about 2-Methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 123-75-1
pyrrolidine

: 86685-04-3
2-methyl-N-(3-phenyl-5-isoxazolyl)propenamide

: 86683-61-6,86685-00-9,86685-01-0
2-methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

Guidance literature:: In ethanol; for 8h; Heating;
DOI:10.1248/cpb.34.1634

Reference yield:

: 4369-55-5
3-phenyl-isoxazol-5-ylamine

: 86683-61-6,86685-00-9,86685-01-0
2-methyl-N-(3-phenyl-5-isoxazolyl)-3-pyrrolidinopropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / pyridine / CHCl₃ / 2 h / -5 °C

2: 88 percent / ethanol / 8 h / Heating

With pyridine; In ethanol; chloroform;
DOI:10.1248/cpb.34.1634