Iferanserin

Base Information

Chemical Name:Iferanserin
CAS No.:58754-46-4
Molecular Formula:C23H28 N2 O
Molecular Weight:348.48
Hs Code.:
UNII:NWR3BEB8PA
DSSTox Substance ID:DTXSID101030346
Wikipedia:Iferanserin
Wikidata:Q5991157
NCI Thesaurus Code:C90945
Metabolomics Workbench ID:152801
ChEMBL ID:CHEMBL3989686
Mol file:58754-46-4.mol

Synonyms:iferanserin

Suppliers and Price of Iferanserin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Iferanserin

Chemical Property:

Vapor Pressure:1.41E-11mmHg at 25°C
Boiling Point:536.4°C at 760 mmHg
Flash Point:278.2°C
PSA：32.34000
Density:1.096g/cm³
LogP:4.76630
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:348.220163521
Heavy Atom Count:26
Complexity:455

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCCC1CCC2=CC=CC=C2NC(=O)C=CC3=CC=CC=C3
Isomeric SMILES:CN1CCCC[C@H]1CCC2=CC=CC=C2NC(=O)/C=C/C3=CC=CC=C3
Recent ClinicalTrials:Efficacy and Safety Study to Treat Subjects With Symptomatic Internal Hemorrhoids

Technology Process of Iferanserin

There total 6 articles about Iferanserin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 58754-46-4
(S)-2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide

Guidance literature:

Reference yield:

: 1360685-63-7
(S)-[2-(o-aminophenethyl)-1-methylpiperidine dibenzoyl-L-tartrate]

: 102-92-1,17082-09-6
cinnamoyl chloride

: 58754-46-4
(S)-2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide

Guidance literature:: (S)-[2-(o-aminophenethyl)-1-methylpiperidine dibenzoyl-L-tartrate]; With sodium hydrogencarbonate; In water; ethyl acetate;

cinnamoyl chloride; With potassium carbonate; In ethyl acetate; for 14h; Reflux;

Reference yield:

: 552-89-6
2-nitro-benzaldehyde

: 58754-46-4
(S)-2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetic anhydride / 27 h / Inert atmosphere; Reflux

2.1: acetone / 18 h / Inert atmosphere; Reflux

3.1: hydrogen / palladium 10% on activated carbon / methanol

4.1: sodium hydroxide / ethyl acetate; water

4.2: 20 °C

5.1: sodium hydrogencarbonate / ethyl acetate; water

5.2: 14 h / Reflux

With hydrogen; acetic anhydride; sodium hydrogencarbonate; sodium hydroxide; palladium 10% on activated carbon; In methanol; water; ethyl acetate; acetone;