1360685-63-7

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 109-06-8 α-picoline 
• 210282-36-3 2-(o-aminophenethyl)-1-methylpiperidine hydroiodide 
• 2743-38-6 O,O'-dibenzoyl-L-tartaric acid 
• 50385-24-5 2-(o-nitrostyryl)pyridine 
• 77340-84-2 2-(o-nitrostyryl)-pyridine 
• 43027-22-1 1-methyl-2-(2-nitro-trans-styryl)-pyridinium; iodide 

Downstream Products

• 58754-46-4 (S)-2'-[2-(1-methyl-2-piperidyl)ethyl]cinnamanilide 
• 62370-16-5 (S)-2-[2-(1-methyl-2-piperidinyl)ethyl]-benzenamine 

Relevant academic research and scientific papers

Development of a scalable synthesis of a serotonin receptor antagonist

An efficient process was developed for the manufacture of MSA100, a serotonin receptor antagonist, via a five-step synthetic route furnishing a high quality of active pharmaceutical ingredient. Highlights of this synthesis include: (1) replacing carcinoge

METHODS AND COMPOSITIONS FOR TREATING HEMORRHOIDS WHILE PROVIDING LOCAL ANESTHETIC AND ANTI-INFLAMMATORY EFFECTS

The present invention relates to compositions and methods for treatment of internal and/or external hemorrhoids, wherein the treatment includes topically administering to a subject a composition comprising from 0.3% to 0.7% of S-2'- [2-(1-methyl-2- piperidyl) ethyl] cinnamanilide, wherein the S-2'- [2-(1-methyl-2-piperidyl) ethyl] cinnamanilide not only treats the hemorrhoidal symptoms but exhibits a local anesthetic effect while controlling inflammation in the area of treatment.

METHODS AND COMPOSITIONS FOR TREATING INTERNAL AND EXTERNAL HEMORRHOIDS

The present invention relates to compositions and methods for treatment of internal and/or external hemorrhoids, wherein the treatment includes topically administering to a subject a composition comprising from 0.3% to 0.7% of S-2'- [2-(l-methyl-2- piperi