Quinocarcin

Base Information

Chemical Name:Quinocarcin
CAS No.:84573-33-1
Molecular Formula:C₁₈H₂₂N₂O₄
Molecular Weight:330.384
Hs Code.:
DSSTox Substance ID:DTXSID501004854
Wikidata:Q83000070
Metabolomics Workbench ID:99152
ChEMBL ID:CHEMBL508248
Mol file:84573-33-1.mol

Synonyms:D 52;D-52;isoquinocarcin;KW 2152;KW-2152;quinocarcin;quinocarmycin;quinocarmycin citrate

Suppliers and Price of Quinocarcin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-Quinocarcin
1mg
$ 1430.00

American Custom Chemicals Corporation
QUINOCARCIN 95.00%
5MG
$ 503.36

Total 4 raw suppliers

Chemical Property of Quinocarcin

Chemical Property:

Vapor Pressure:1.08E-11mmHg at 25°C
Boiling Point:521.3°Cat760mmHg
Flash Point:269.1°C
PSA：62.24000
Density:1.41g/cm³
LogP:0.98220
XLogP3:-1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:330.15795719
Heavy Atom Count:24
Complexity:543

Purity/Quality:

95% ^*data from raw suppliers

(-)-Quinocarcin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2CC(C1C3CC4=C(C5N3C2OC5)C(=CC=C4)OC)C(=O)O
Isomeric SMILES:CN1[C@H]2C[C@H]([C@@H]1[C@@H]3CC4=C([C@H]5N3[C@@H]2OC5)C(=CC=C4)OC)C(=O)O
Uses (-)-Quinocarcin are potent antitumor antibiotics that plays a key role in the construction of tetracyclic THIQ-pyrrolidine core scaffold.

Technology Process of Quinocarcin

There total 110 articles about Quinocarcin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 96251-59-1
<5R-(5α,7β,8β,10β,11β,11aβ)>-7-cyano-5,7,8,9,10,11,11a,12-octahydro-4-methoxy-5-(hydroxymethyl)-13-methyl-8,11-iminoazepino<1,2-b>isoquinoline-10-carboxylic acid

: 84573-33-1
(-)-quinocarcin

Guidance literature:: With silver nitrate; In methanol; water; for 4h; Ambient temperature;
DOI:10.1021/ja00076a036

Reference yield: 89.0%

: 96251-59-1,115361-93-8
4-cyano-6-hydroxymethyl-3,12-imino-7-methoxy-13-methyl-1,2,3,4,6,11,11a,12-octahydroazepino<1,2-b>isoquinoline-1-carboxylic acid

: 84573-33-1
(-)-quinocarcin

Guidance literature:: With silver nitrate; In methanol; water;
DOI:10.1021/ja00033a089

Reference yield: 87.0%

: 1030029-43-6
(-)-quinocarcinamide formate

: 84573-33-1
(-)-quinocarcin

Guidance literature:: (-)-quinocarcinamide formate; With ammonia; lithium; In tetrahydrofuran; at -25 ℃; for 0.25h;

With hydrogenchloride; In methanol; water; at 20 ℃; for 2h; pH=6; Further stages.;
DOI:10.1021/ja800662q