2,2-Dichloro-N-ethylacetamide

Base Information

• Chemical Name: 2,2-Dichloro-N-ethylacetamide
• CAS No.: 42275-79-6
• Molecular Formula: C4H7 Cl2 N O
• Molecular Weight: 156.012
• Hs Code.: 2924199090
• European Community (EC) Number: 255-746-1
• DSSTox Substance ID: DTXSID60195103
• Nikkaji Number: J278.376B
• Wikidata: Q83067971
• Mol file: 42275-79-6.mol

Synonyms:2,2-Dichloro-N-ethylacetamide;42275-79-6;EINECS 255-746-1;Acetamide, 2,2-dichloro-N-ethyl-;SCHEMBL10951685;DTXSID60195103;AKOS003872257

Chemical Property of 2,2-Dichloro-N-ethylacetamide

Chemical Property:

• Vapor Pressure: 0.0092mmHg at 25°C
• Boiling Point: 265.4°Cat760mmHg
• Flash Point: 114.3°C
• PSA: 32.59000
• Density: 1.261g/cm³
• LogP: 1.76650
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 154.9904692
• Heavy Atom Count: 8
• Complexity: 84.1

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC(=O)C(Cl)Cl

Technology Process of 2,2-Dichloro-N-ethylacetamide

There total 6 articles about 2,2-Dichloro-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

N,N-dichloroethylamine (24948-83-2) + Trichloroethylene (79-01-6) → Dichloroacetic acid ethylamide (42275-79-6)

Guidance literature:

With oxygen; Heating; Irradiation;

Reference yield:

dichloroacethyl chloride (79-36-7) + ethylamine (75-04-7,85404-22-4) → Dichloroacetic acid ethylamide (42275-79-6)

Guidance literature:

With sodium hydroxide; diethyl ether; at -10 - -5 ℃;

DOI:10.1046/j.1525-139X.2001.00057-2.x

Reference yield:

2-chloro-N-ethylacetamide (105-35-1) → Dichloroacetic acid ethylamide (42275-79-6)

Guidance literature:

With phosphorus pentachloride; und folgende Behandlung mit Wasser;

upstream raw materials:

2-chloro-N-ethylacetamide

N-ethyl-2,2-dichloro-acetimidoyl chloride

dichloroacethyl chloride

ethylamine