Ethylamine

Base Information

• Chemical Name: Ethylamine
• CAS No.: 75-04-7
• Deprecated CAS: 43031-21-6,85404-16-6,85404-22-4,85404-16-6,85404-22-4
• Molecular Formula: C2H7N
• Molecular Weight: 45.0843
• Hs Code.: 2921.19
• European Community (EC) Number: 200-834-7
• ICSC Number: 0153
• UN Number: 1036
• UNII: YG6MGA6AT5
• DSSTox Substance ID: DTXSID8025678
• Nikkaji Number: J1.437K
• Wikipedia: Ethylamine
• Wikidata: Q411119
• Metabolomics Workbench ID: 42262
• ChEMBL ID: CHEMBL14449
• Mol file: 75-04-7.mol

Synonyms:ethylamine;ethylamine hydrobromide;ethylamine hydrochloride;ethylamine, 14C-labeled

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Chemical Property of Ethylamine

Chemical Property:

• Appearance/Colour: light yellow liquid
• Melting Point: -81 °C
• Refractive Index: n20/D 1.384
• Boiling Point: 14.2 °C at 760 mmHg
• PKA: 10?+-.0.10(Predicted)
• Flash Point: -17 °C
• PSA: 26.02000
• Density: 0.691 g/cm³
• LogP: 0.66530
• Water Solubility.: miscible
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 45.057849228
• Heavy Atom Count: 3
• Complexity: 2.8
• Transport DOT Label: Flammable Gas

Purity/Quality:

Safty Information:

• Pictogram(s): F+,Xi,T,F
• Hazard Codes: F+:Highly flammable
• Statements: R12:; R36/37:
• Safety Statements: S16:; S26:; S29:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCN
• Inhalation Risk: A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
• Effects of Short Term Exposure: The substance is severely irritating to the eyes and respiratory tract. Rapid evaporation of the liquid may cause frostbite.

Technology Process of Ethylamine

There total 511 articles about Ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

N-ethyl-N-hydroxy-ethanamine (3710-84-7) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-Ethylmethylamine (624-78-2) + ethylamine (75-04-7,85404-22-4) + acetaldehyde (75-07-0,9002-91-9)

Guidance literature:

With phosphorus pentachloride; In toluene; at 18 - 20 ℃; Mechanism; Product distribution; object of study: Stieglitz rearrangement (prototype);

Reference yield: 50.0%

2-(ethylamino)-2-methylpropanol hydrochloride (82922-13-2) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethylamine (75-04-7,85404-22-4) + 2-Amino-2-methyl-1-propanol (124-68-5) + acetone (67-64-1)

Guidance literature:

With water; at 25 ℃; Further byproducts given; anodic oxidation, pH 10, carbonate buffer;

Reference yield: 50.0%

2-(ethylamino)-2-methylpropanol hydrochloride (82922-13-2) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethylamine (75-04-7,85404-22-4) + 2-Amino-2-methyl-1-propanol (124-68-5) + acetaldehyde (75-07-0,9002-91-9) + acetone (67-64-1)

Guidance literature:

With water; at 25 ℃; Product distribution; Mechanism; anodic oxidation, carbonate buffer, pH 10; effect of substituents investigated with different types of β-alkanolamines;

upstream raw materials:

2,4,6-trimethyl-[1,3,5]triazinane

acetamide

ethanol

sodium ethanolate

Downstream raw materials:

ethyldiethanolamine

2-(Ethylamino)ethanol

1-ethylpyrrolidine

N-Diphenylmethylen(ethyl)amin

Refernces

• 1、 Tokunaga et al.. "-". . p. 1050. Retrieved 1972.
• 2、 Tsunashima, Shigeru,Hamada, Jun-ichi,Hotta, Mitsuhiro,Sato, Shin. "The Reactions of NH(a1Δ) with Ethane, Propane, and Isobutane in the Liquid Phase". . p. 2443 - 2447. Retrieved 1980.
• 3、 Li, Hui,Zhang, Dieqing,Li, Guisheng,Xu, Ye,Lu, Yunfeng,Li, Hexing. "Mesoporous Ni-B amorphous alloy microspheres with tunable chamber structure and enhanced hydrogenation activity". . p. 791 - 793. Retrieved 2010.
• 4、 Crocomo,Fowden. "-". . p. 537,540. Retrieved 1970.
• 5、 Qiao, Chenxia,Jia, Wenlan,Zhong, Qiming,Liu, Bingyu,Zhang, Yifu,Meng, Changgong,Tian, Fuping. "MOF-Derived Cu-Nanoparticle Embedded in Porous Carbon for the Efficient Hydrogenation of Nitroaromatic Compounds". . p. 3394 - 3401. Retrieved 2020/05/19.
• 6、 Liu, Lei,Li, Jifan,Ai, Yongjian,Liu, Yuhong,Xiong, Jialiang,Wang, Hongdong,Qiao, Yijun,Liu, Wenrui,Tan, Shanchao,Feng, Shaofei,Wang, Kunpeng,Sun, Hongbin,Liang, Qionglin. "A ppm level Rh-based composite as an ecofriendly catalyst for transfer hydrogenation of nitriles: Triple guarantee of selectivity for primary amines". . p. 1390 - 1395. Retrieved 2019/03/26.