N-acetyl-2-carboxy Benzenesulfonamide

Base Information

Chemical Name:N-acetyl-2-carboxy Benzenesulfonamide
CAS No.:849067-18-1
Molecular Formula:C₉H₉NO₅S
Molecular Weight:243.24
Hs Code.:
Mol file:849067-18-1.mol

Synonyms:

Suppliers and Price of N-acetyl-2-carboxy Benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
N-acetyl-2-carboxy Benzenesulfonamide ≥98%
10mg
$ 114.00

Cayman Chemical
N-acetyl-2-carboxy Benzenesulfonamide ≥98%
5mg
$ 64.00

Cayman Chemical
N-acetyl-2-carboxy Benzenesulfonamide ≥98%
1mg
$ 15.00

Cayman Chemical
N-acetyl-2-carboxy Benzenesulfonamide ≥98%
50mg
$ 492.00

ApexBio Technology
N-acetyl-2-carboxyBenzenesulfonamide
10mg
$ 145.00

AK Scientific
2-[(Acetylamino)sulfonyl]-benzoicacid
50mg
$ 714.00

AK Scientific
2-[(Acetylamino)sulfonyl]-benzoicacid
1mg
$ 117.00

Total 3 raw suppliers

Chemical Property of N-acetyl-2-carboxy Benzenesulfonamide

Chemical Property:

Melting Point:178-180 °C
PKA:2.79±0.36(Predicted)
PSA：108.92000
Density:1.463±0.06 g/cm3(Predicted)
LogP:1.68130
Solubility.:≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide

Purity/Quality:

95% ^*data from raw suppliers

N-acetyl-2-carboxy Benzenesulfonamide ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23. In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 μM and 0.25 μM, respectively, than aspirin with IC50 values of 0.35 μM and 2.4 μM, respectively.

Technology Process of N-acetyl-2-carboxy Benzenesulfonamide

There total 3 articles about N-acetyl-2-carboxy Benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 27200-69-7
N-acetyl-2-methylbenzenesulfonamide

: 849067-18-1
2-(N-acetylsulfamoyl)benzoic acid

Guidance literature:: With sodium hydroxide; potassium permanganate; In water; at 60 ℃; for 6h;
DOI:10.1016/j.bmc.2005.01.039

Reference yield:

: 88-19-7
methyl 2-(aminosulfonyl)benzoate

: 849067-18-1
2-(N-acetylsulfamoyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 4-dimethylaminopyridine; pyridine / 6 h / 25 °C

2: 63 percent / KMnO₄; NaOH / H₂O / 6 h / 60 °C

With pyridine; dmap; sodium hydroxide; potassium permanganate; In water;
DOI:10.1016/j.bmc.2005.01.039