Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-

Base Information

Chemical Name:Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-
CAS No.:154229-21-7
Molecular Formula:C24H29 N O
Molecular Weight:347.5
Hs Code.:
UNII:Z2L6XS2R7H
DSSTox Substance ID:DTXSID90934961
Nikkaji Number:J686.891F
Wikipedia:%CE%944-Abiraterone
Wikidata:Q30647364
Pharos Ligand ID:RFF96QRACWS8
ChEMBL ID:CHEMBL132778
Mol file:154229-21-7.mol

Synonyms:17-(3-pyridyl)androsta-5,16-dien-3-one;CB 7627;CB-7627;CB7627

Suppliers and Price of Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
17-(3-Pyridinyl)-androsta-4,16-dien-3-one
25mg
$ 1390.00

Sigma-Aldrich
Abiraterone D4A metabolite ≥98% (HPLC)
5mg
$ 98.60

Sigma-Aldrich
Abiraterone D4A metabolite ≥98% (HPLC)
25mg
$ 399.00

Medical Isotopes, Inc.
17-(3-Pyridinyl)-androsta-4,16-dien-3-one
2.5 mg
$ 650.00

DC Chemicals
Abiraterone(D4A) >98%
100 mg
$ 600.00

DC Chemicals
Abiraterone(D4A) >98%
250 mg
$ 1100.00

DC Chemicals
Abiraterone(D4A) >98%
1 g
$ 2200.00

ChemScene
D4-abiraterone 99.27%
25mg
$ 310.00

ChemScene
D4-abiraterone 99.27%
10mg
$ 140.00

ChemScene
D4-abiraterone 99.27%
5mg
$ 80.00

Total 20 raw suppliers

Chemical Property of Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-

Chemical Property:

Vapor Pressure:2.63E-10mmHg at 25°C
Boiling Point:504.6°Cat760mmHg
PKA:5.32±0.12(Predicted)
Flash Point:259.9°C
PSA：29.96000
Density:1.14g/cm³
LogP:5.60680
Storage Temp.:2-8°C
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:347.224914549
Heavy Atom Count:26
Complexity:676

Purity/Quality:

97% ^*data from raw suppliers

17-(3-Pyridinyl)-androsta-4,16-dien-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(=O)C=C1CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C
Isomeric SMILES:C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C
Uses 17-(3-Pyridinyl)-androsta-4,16-dien-3-one is a possible steroidal inhibitor of human cytochrome P 45017α-hydroxylase-C17,20-lyase.

Technology Process of Androsta-4,16-dien-3-one, 17-(3-pyridinyl)-

There total 16 articles about Androsta-4,16-dien-3-one, 17-(3-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 154229-19-3
abiraterone

: 154229-21-7
17-(3-pyridine)-4,16-dieneandrost-3-one

Guidance literature:: With aluminum isopropoxide; In toluene; butanone; Inert atmosphere; Reflux;

Reference yield: 71.0%

: 154229-38-6
3-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-17-(3-pyridyl)androsta-3,5,16-triene

: 154229-21-7
17-(3-pyridine)-4,16-dieneandrost-3-one

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; ethanol; at 65 ℃; for 48h;
DOI:10.1021/jm00013a022

Reference yield: 39.0%

: 89878-14-8
3-Diethylboranylpyridine

: 100772-35-8
17-iodoandrosta-4,16-dien-3-one

: 154229-21-7
17-(3-pyridine)-4,16-dieneandrost-3-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In tetrahydrofuran; water; for 7h; Inert atmosphere; Reflux;
DOI:10.1016/j.jsbmb.2014.01.013