[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate

Base Information

Chemical Name:[(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate
CAS No.:61397-61-3
Molecular Formula:C15H16Cl2N2O5S
Molecular Weight:407.274
Hs Code.:
Nikkaji Number:J276.331A
Mol file:61397-61-3.mol

Synonyms:

Suppliers and Price of [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLANE-4-YLMETHYL METHANESULFONATE 95.00%
20G
$ 3234.00

Total 20 raw suppliers

Chemical Property of [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate

Chemical Property:

Vapor Pressure:8.03E-15mmHg at 25°C
Melting Point:92-94 °C
Refractive Index:1.626
Boiling Point:624.1 °C at 760 mmHg
PKA:6.88±0.12(Predicted)
Flash Point:331.3 °C
PSA：88.03000
Density:1.52g/cm³
LogP:3.51530
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:406.0156982
Heavy Atom Count:25
Complexity:561

Purity/Quality:

97% ^*data from raw suppliers

CIS-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLANE-4-YLMETHYL METHANESULFONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)OCC1COC(O1)(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl
Isomeric SMILES:CS(=O)(=O)OC[C@H]1CO[C@](O1)(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl

Technology Process of [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate

There total 6 articles about [(2R,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 61397-58-8,61441-65-4,68684-88-8,68685-07-4,84682-23-5
trans-2-(2,4-Dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolane-4-methanol

: 124-63-0
methanesulfonyl chloride

: 61397-61-3,68473-14-3,133345-20-7
trans-<2-(2,4-Dichlorophenyl)-2-<1H-imidazol-1-yl>methyl-(1,3-dioxolan-4-yl)>methyl methanesulfonate

Guidance literature:: In pyridine; for 18h;

Reference yield:

: 83086-42-4
Benzoic acid (2R,4R)-2-(2,4-dichloro-phenyl)-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethyl ester; compound with nitric acid

: 61397-61-3
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)methyl-(1,3-dioxolan-4-yl)]methyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / 6N NaOH / dioxane / 1.5 h / Heating

2: pyridine

With sodium hydroxide; In 1,4-dioxane; pyridine;