Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)

Base Information

Chemical Name:Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)
CAS No.:93778-56-4
Molecular Formula:C67H58 Cl N8 O14 P
Molecular Weight:1265.67
Hs Code.:

Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)

Synonyms:

Suppliers and Price of Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI)

There total 10 articles about Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-P-(4-chlorophenyl)-2'-deoxycytidylyl-(3'®5')-N-benzoyl-2'-deoxy-,3'-benzoate (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67219-55-0
4-N-Benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidine

: 93778-56-4
N-benzoyl-P-(4-chlorophenyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidylyl-(3'->5')-N-benzoyl-2'-deoxyadenosine 3'-benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) pyridine; 2.) 5percent aq. NH₄HCO₃ / 1.) dioxane, 30 min at room temp.; 2.) dioxane, cooling

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

With pyridine; 1-mesitylsulfonyl-1H-tetrazole; ammonium bicarbonate; In pyridine;

Reference yield:

: 69507-62-6
(p-chlorophenyl) (β-cyanoethyl) phosphorochloridate

: 93778-56-4
N-benzoyl-P-(4-chlorophenyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidylyl-(3'->5')-N-benzoyl-2'-deoxyadenosine 3'-benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: 1-methylimidazole / acetonitrile / 2 h / 20 °C

2: triethylamine

3: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

With 1-methyl-1H-imidazole; 1-mesitylsulfonyl-1H-tetrazole; triethylamine; In pyridine; acetonitrile;

Reference yield:

: 57777-87-4
N⁴-benzoyl-5'-O-(p,p'-dimethoxytrityl)deoxycytidine 3'-<(p-chlorophenyl)(β-cyanoethyl)phosphate>

: 93778-56-4
N-benzoyl-P-(4-chlorophenyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)cytidylyl-(3'->5')-N-benzoyl-2'-deoxyadenosine 3'-benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine

2: 1-(mesitylsulfonyl)tetrazole / pyridine / 1 h / Ambient temperature

With 1-mesitylsulfonyl-1H-tetrazole; triethylamine; In pyridine;