Benzene, 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundec yl)-4-methoxy-

Base Information

• Chemical Name: Benzene, 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundec yl)-4-methoxy-
• CAS No.: 849354-60-5
• Molecular Formula: C18H12F17IO
• Molecular Weight: 694.17
• Mol file: 849354-60-5.mol

Synonyms:

Chemical Property of Benzene, 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundec yl)-4-methoxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundec yl)-4-methoxy-

There total 1 articles about Benzene, 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundec yl)-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

Estragole (140-67-0) + 1-iodoheptadecafluorooctane (507-63-1) → 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundecyl)-4-methoxybenzene (849354-60-5)

Guidance literature:

With trimethylaluminum; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In hexane; dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/jo048001n

Reference yield: 80.8%

1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundecyl)-4-methoxybenzene (849354-60-5) → 1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-4-methoxybenzene (849354-61-6)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 12h; Heating;

DOI:10.1021/jo048001n

Reference yield:

1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-3-iodoundecyl)-4-methoxybenzene (849354-60-5) → 4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-1-isopropoxy-2-vinylbenzene

Guidance literature:

Multi-step reaction with 5 steps

1: 80.8 percent / tributyltin hydride; AIBN / benzene / 12 h / Heating

2: 87.7 percent / BBr₃*Me₂S / 1,2-dichloro-ethane / 12 h / Heating

3: 93.8 percent / sodium hydride / tetrahydrofuran; dimethylformamide / 16 h / 20 °C

4: 94.4 percent / acetic acid; bromine / CH₂Cl₂ / 2 h / 20 °C

5: 63.8 percent / Pd(PPh₃)4 / toluene / 96 h / Heating

With boron tribromide-dimethyl sulfide complex; 2,2'-azobis(isobutyronitrile); bromine; tri-n-butyl-tin hydride; sodium hydride; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1021/jo048001n

upstream raw materials:

Estragole

1-iodoheptadecafluorooctane

Downstream raw materials:

1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-4-methoxybenzene

1-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-4-isopropoxybenzene

2-bromo-4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-1-isopropoxybenzene

4-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)phenol