Boc-Phe(3,5-Me)-OH

Base Information

Chemical Name:Boc-Phe(3,5-Me)-OH
CAS No.:849440-33-1
Molecular Formula:C16H23NO4
Molecular Weight:293.363
Hs Code.:
DSSTox Substance ID:DTXSID101181836
Nikkaji Number:J2.130.525A
Mol file:849440-33-1.mol

Synonyms:Boc-Phe(3,5-Me)-OH;849440-33-1;(S)-2-((TERT-BUTOXYCARBONYL)AMINO)-3-(3,5-DIMETHYLPHENYL)PROPANOIC ACID;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(3,5-dimethylphenyl)propanoic acid;SCHEMBL2132063;(2S)-3-(3,5-dimethylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid;YTXNDRYCIWRWPG-ZDUSSCGKSA-N;DTXSID101181836;ZIB44033;MFCD09841968;AKOS030632758;GS-7201;CS-0158521;Y10901;n-(tert-butoxycarbonyl)-3,5-dimethyl-l-phenylalanine;N-[(1,1-Dimethylethoxy)carbonyl]-3,5-dimethyl-L-phenylalanine;(S)-2-((t-Butoxycarbonyl)amino)-3-(3,5-dimethylphenyl)propanoic acid (Boc-L-Phe(3,5-Me2)-OH)

Suppliers and Price of Boc-Phe(3,5-Me)-OH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Iris Biotech GmbH
Boc-L-Phe(3,5-Me2)-OH
1 g
$ 1080.00

Iris Biotech GmbH
Boc-L-Phe(3,5-Me2)-OH
250 mg
$ 405.00

Crysdot
Boc-Phe(3,5-Me)-OH 97%
250mg
$ 297.00

Crysdot
Boc-Phe(3,5-Me)-OH 97%
1g
$ 743.00

Chemenu
(S)-2-((tert-Butoxycarbonyl)amino)-3-(3,5-dimethylphenyl)propanoicacid 97%
1g
$ 701.00

Ambeed
Boc-Phe(3,5-Me)-OH 97%
250mg
$ 188.00

Ambeed
Boc-Phe(3,5-Me)-OH 97%
100mg
$ 94.00

Activate Scientific
Boc-Phe(3,5-Me)-OH 97%
1 g
$ 1006.00

Activate Scientific
Boc-Phe(3,5-Me)-OH 97%
250 mg
$ 448.00

Activate Scientific
Boc-Phe(3,5-Me)-OH 97%
100 mg
$ 240.00

Total 7 raw suppliers

Chemical Property of Boc-Phe(3,5-Me)-OH

Chemical Property:

Melting Point:106-110 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
Boiling Point:452.2±45.0 °C(Predicted)
PKA:3.94±0.10(Predicted)
PSA：75.63000
Density:1.123±0.06 g/cm3(Predicted)
LogP:3.21470
Storage Temp.:2-8°C
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:293.16270821
Heavy Atom Count:21
Complexity:365

Purity/Quality:

98% ^*data from raw suppliers

Boc-L-Phe(3,5-Me2)-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)CC(C(=O)O)NC(=O)OC(C)(C)C)C
Isomeric SMILES:CC1=CC(=CC(=C1)C[C@@H](C(=O)O)NC(=O)OC(C)(C)C)C

Technology Process of Boc-Phe(3,5-Me)-OH

There total 3 articles about Boc-Phe(3,5-Me)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

: 1241680-65-8
3',5'-dimethyl-L-phenylalanine

: 24424-99-5
di-tert-butyl dicarbonate

: 849440-33-1,1213338-17-0
N^α-tert-butyloxycarbonyl-3',5'-dimethyl-L-phenylalanine

Guidance literature:: With triethylamine; In 1,4-dioxane; water; at 20 ℃; for 2h;
DOI:10.1021/jm061238m

Reference yield:

: 27129-86-8
1-bromomethyl-3,5-dimethylbenzene

: 24424-99-5
di-tert-butyl dicarbonate

: nickelous 2-[(E)-[[2-[(2S)-1-benzylpyrrolidine-2-carbonyl]azanidylphenyl]-phenylmethylene]amino]acetate

: 849440-33-1,1213338-17-0
N^α-tert-butyloxycarbonyl-3',5'-dimethyl-L-phenylalanine

: 96293-17-3,105024-93-9,105112-33-2
(S)-N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide

Guidance literature:: 1-bromomethyl-3,5-dimethylbenzene; nickelous 2-[(E)-[[2-[(2S)-1-benzylpyrrolidine-2-carbonyl]azanidylphenyl]-phenylmethylene]amino]acetate; With sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In methanol; at 70 ℃;

di-tert-butyl dicarbonate; With sodium carbonate; In 1,4-dioxane; water; at 20 ℃;
DOI:10.3987/COM-04-S(P)41