Estradiol 3-tetrahydropyranyl ether

Base Information

Chemical Name:Estradiol 3-tetrahydropyranyl ether
CAS No.:41781-86-6
Molecular Formula:C23H32O3
Molecular Weight:356.4984
Hs Code.:
NSC Number:86473
UNII:2UC9XAN8CV
DSSTox Substance ID:DTXSID00292923
Wikipedia:Estradiol_3-tetrahydropyranyl_ether
Wikidata:Q82031431
ChEMBL ID:CHEMBL472508
Mol file:41781-86-6.mol

Synonyms:Estradiol 3-tetrahydropyranyl ether;41781-86-6;2UC9XAN8CV;NSC-86473;UNII-2UC9XAN8CV;CHEMBL472508;Estra-1,3,5(10)-trien-17beta-ol, 3-((tetrahydropyran-2-yl)oxy)-;(17beta)-3-((Tetrahydro-2H-pyran-2-yl)oxy)estra-1,3,5(10)-trien-17-ol;Estra-1,3,5(10)-trien-17-ol, 3-((tetrahydro-2H-pyran-2-yl)oxy)-, (17beta)-;NSC86473;DTXSID00292923;BDBM50244327;17.beta.-Estradiol, 3-(tetrahydropyran-2-yl ether);Estra-1,5(10)-trien-17.beta.-ol, 3-[(tetrahydropyran-2-yl)oxy]-;(17.BETA.)-3-((TETRAHYDRO-2H-PYRAN-2-YL)OXY)ESTRA-1,3,5(10)-TRIEN-17-OL;ESTRA-1,3,5(10)-TRIEN-17-OL, 3-((TETRAHYDRO-2H-PYRAN-2-YL)OXY)-, (17.BETA.)-;ESTRA-1,3,5(10)-TRIEN-17.BETA.-OL, 3-((TETRAHYDROPYRAN-2-YL)OXY)-;(8R,9S,13S,14S,17S)-13-methyl-3-(tetrahydro-2H-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol

Suppliers and Price of Estradiol 3-tetrahydropyranyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Estradiol 3-tetrahydropyranyl ether

Chemical Property:

Vapor Pressure:2.08E-11mmHg at 25°C
Boiling Point:514.4°Cat760mmHg
Flash Point:264.9°C
Density:1.143g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:356.23514488
Heavy Atom Count:26
Complexity:508

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC5CCCCO5
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)OC5CCCCO5

Technology Process of Estradiol 3-tetrahydropyranyl ether

There total 3 articles about Estradiol 3-tetrahydropyranyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 50-28-2
estradiol

: 3589-91-1
3,17β-bis(2-tetrahydropyranyloxy)estra-1,3,5(10)-triene

: 41781-86-6
Estradiol-3-tetrahydropyranylether

Guidance literature:: With basic resin Amberlite IRA-400 (iodide form); In dichloromethane; at 20 ℃; for 0.133333h;

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 53-16-7,474-84-0,517-06-6,1225-03-2,4413-09-6,4680-83-5,5285-27-8,15426-98-9,17337-44-9,19973-76-3,35937-97-4,35937-99-6,35938-00-2,94424-34-7,101976-76-5,107910-81-6
estrone

: 21231-98-1,21231-99-2,41781-86-6
3-(2-tetrahydropyranyloxy)-1,3,5(10)estratrien-17β-ol

Guidance literature:: With bis(methoxyethoxy) aluminum hydride; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1).3.0 hrs., r.t., 2) 2.0 hrs. reflux, benzene;