Spiro[2.5]octan-6-ylmethanol

Base Information

• Chemical Name: Spiro[2.5]octan-6-ylmethanol
• CAS No.: 849671-56-3
• Molecular Formula: C9H16O
• Molecular Weight: 140.225
• Hs Code.: 2906199090
• DSSTox Substance ID: DTXSID60705241
• Wikidata: Q82638034
• Mol file: 849671-56-3.mol

Synonyms:Spiro[2.5]octan-6-ylmethanol;849671-56-3;Spiro[2.5]oct-6-yl-methanol;{spiro[2.5]octan-6-yl}methanol;(Spiro[2.5]octan-6-yl)methanol;spiro[2.5]oct-6-ylmethanol;SCHEMBL3025238;DTXSID60705241;CPOBXDZHERXVFP-UHFFFAOYSA-N;MFCD11501505;AKOS006323330;DS-18201;CS-0055026;FT-0709777;EN300-317616;A863854;F2147-8523

Chemical Property of Spiro[2.5]octan-6-ylmethanol

Chemical Property:

• PSA: 20.23000
• LogP: 1.94910
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 140.120115130
• Heavy Atom Count: 10
• Complexity: 117

Purity/Quality:

97% ^*data from raw suppliers

Spiro[2.5]octan-6-ylmethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2(CCC1CO)CC2

Technology Process of Spiro[2.5]octan-6-ylmethanol

There total 5 articles about Spiro[2.5]octan-6-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethyl spiro[2.5]octane-6-carboxylate → spiro[2.5]octan-6-ylmethanol (849671-56-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;

Reference yield: 75.0%

→ spiro[2.5]octan-6-ylmethanol (849671-56-3)

Guidance literature:

Reference yield: 34.0%

diiodomethane (75-11-6) + 4-methylene-1-cyclohexanemethanol (1004-24-6) → spiro[2.5]octan-6-ylmethanol (849671-56-3)

Guidance literature:

With diethylzinc; In toluene; at 20 - 60 ℃; for 20h;

DOI:10.1016/j.bmcl.2008.07.011

upstream raw materials:

diiodomethane

4-methylene-1-cyclohexanemethanol

ethyl 4-methylidenecyclohexanecarboxylate

ethyl 4-oxocyclohexane-1-carboxylate

Downstream raw materials:

C₁₆H₂₂O₃S