1004-24-6

Usage

Uses

Used in Fragrance Industry:
4-METHYLENECYCLOHEXYLMETHANOL is used as a fragrance ingredient for its pleasant aroma, primarily in personal care products and cosmetics. It adds a subtle scent to these products, enhancing their appeal to consumers.
Used in Flavor Industry:
In the flavor industry, 4-METHYLENECYCLOHEXYLMETHANOL is used as a flavoring agent to impart a slightly sweet taste to various food and beverage products, contributing to their overall flavor profile.
Used in Pharmaceutical Industry:
4-METHYLENECYCLOHEXYLMETHANOL is utilized in the synthesis of other chemicals, including pharmaceuticals. It serves as a key intermediate in the production of various medications, playing a crucial role in the development of new drugs.
Used in Agrochemical Industry:
4-METHYLENECYCLOHEXYLMETHANOL is also used in the synthesis of agrochemicals, contributing to the development of pesticides and other agricultural products that help protect crops and enhance agricultural productivity.
Safety Precautions:
Due to its potential as a skin irritant, it is essential to take safety precautions when handling and using 4-METHYLENECYCLOHEXYLMETHANOL. This includes wearing appropriate personal protective equipment, such as gloves and goggles, and ensuring proper ventilation in the workspace to minimize exposure risks.

InChI:InChI=1/C8H14O/c1-7-2-4-8(6-9)5-3-7/h8-9H,1-6H2

Upstream product

• 115506-09-7 trans-1,4-bis-methanesulfonyloxymethyl-cyclohexane 
• 116076-50-7 (1,4-cis-cyclohexanediyl)bis(methylene)dimethanesultonate 
• 3236-47-3 (1s,4s)-cyclohexane-1,4-diyldimethanol 
• 3399-21-1 cis-dimethyl 1,4-cyclohexanedicarboxylate 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 3618-04-0 4-hydroxycyclohexyl carboxylic acid ethyl ester 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 145576-28-9 ethyl 4-methylidenecyclohexanecarboxylate 
• 934-69-0 4-methylenecyclohexanecarboxylic acid 

Downstream Products

• 73588-14-4 (E)-4-(4-Hydroxymethyl-cyclohex-1-enyl)-but-2-enoic acid methyl ester 
• 849671-56-3 spiro[2.5]octan-6-ylmethanol 
• 147151-56-2 Iodo(4-methylenecyclohexyl)acetonitrile 
• 71707-69-2 (4-Methylenecyclohexyl)acetonitrile 
• 76825-09-7 (4-Methylenecyclohexylmethyl)bromide 
• 2808-80-2 4-methyl-1-methylidenecyclohexane 

Relevant academic research and scientific papers

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

INHIBITORS OF CATHEPSIN S

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.

Synthesis of Bridgehead-Substituted Bicycloheptanes by Radical Cyclization

A kinetic investigation shows that the rate of cyclization (kC) of the (4-methylenecyclohexyl)methyl radical 3 at 25 deg C is 4.4 x 102 s-1, which is considerably slower than that (2.3 x 105 s-1) of the parent 5-hexenyl radical.The energy of activation for the process 3 -> 4 is 12.8 kcal mol-1, which is in excellent agreement with theoretical values derived from force-field calculations.Ring-closure of appropriately substituted (4-methylenecyclohexyl)methyl radical precursors allows the synthesis of bicycloheptyl systems with useful functionality at the bridgehead to be achieved readily and in high yield.An interesting example is given of the application of an iodine-atom-transfer cyclization to the synthesis of a bicycloheptane functionalized at C7 and C1.