4,6-Dihydroxy-5-formylpyrimidine

Base Information

• Chemical Name: 4,6-Dihydroxy-5-formylpyrimidine
• CAS No.: 14256-99-6
• Molecular Formula: C₅H₄N₂O₃
• Molecular Weight: 140.098
• Hs Code.: 2933599090
• Mol file: 14256-99-6.mol

Synonyms:5-Pyrimidinecarboxaldehyde,1,4-dihydro-6-hydroxy-4-oxo- (9CI);5-Pyrimidinecarboxaldehyde, 1,6-dihydro-4-hydroxy-6-oxo-(8CI);6-Oxo-4-hydroxy-3,6-dihydropyrimidine-5-carboxaldehyde;NSC 338562;

Chemical Property of 4,6-Dihydroxy-5-formylpyrimidine

Chemical Property:

• PSA: 83.31000
• Density: 1.63g/cm3
• LogP: -0.29970
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

4,6-Dihydroxy-5-formylpyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-Dihydroxy-5-formylpyrimidine

There total 5 articles about 4,6-Dihydroxy-5-formylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

5-[1-Dimethylamino-meth-(Z)-ylidene]-1H-pyrimidine-4,6-dione; hydrochloride → 4,6-dioxo-1,4,5,6-tetrahydro-pyrimidine-5-carbaldehyde (14256-99-6)

Guidance literature:

hydrolysis;

Reference yield:

N-((4,6-dihydroxypyrimidin-5-yl)methylene)-N-methylmethylammonium chloride salt (15263-75-9) → 4,6-dihydroxy-5-formylpyrimidine (14256-99-6)

Guidance literature:

With water; at 20 - 30 ℃; for 18h;

Reference yield:

→ 4,6-dioxo-1,4,5,6-tetrahydro-pyrimidine-5-carbaldehyde (14256-99-6)

Guidance literature:

Imoniumchlorid 2a, W.;

upstream raw materials:

N-((4,6-dihydroxypyrimidin-5-yl)methylene)-N-methylmethylammonium chloride salt

Downstream raw materials:

2,6-dichloro-pyrimidine carbaldehyde

5-aminomethylenebarbituric acid