2-(2,6-DICHLORO-PHENYL)-ACETAMIDINE

Base Information

• Chemical Name: 2-(2,6-DICHLORO-PHENYL)-ACETAMIDINE
• CAS No.: 78622-21-6
• Molecular Formula: C8H8 Cl2 N2
• Molecular Weight: 203.07
• Hs Code.: 2925290090
• Mol file: 78622-21-6.mol

Synonyms:2-(2,6-Dichlorophenyl)acetamidine;IPRO 2

Chemical Property of 2-(2,6-DICHLORO-PHENYL)-ACETAMIDINE

Chemical Property:

• PSA: 49.87000
• LogP: 3.27190
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

2-(2,6-Dichlorophenyl)acetimidamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,6-DICHLORO-PHENYL)-ACETAMIDINE

There total 1 articles about 2-(2,6-DICHLORO-PHENYL)-ACETAMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichlorophenylacetonitrile (3215-64-3) → 2,6-dichlorobenzeneethanimidamide (78622-21-6)

Guidance literature:

With trimethylaluminum; ammonium chloride; In toluene;

DOI:10.1016/S0960-894X(01)00410-3

Reference yield: 99.0%

5-nitro-1,2,3-triazine + 2,6-dichlorobenzeneethanimidamide (78622-21-6) → 2-(2,6-dichlorobenzyl)-5-nitropyrimidine

Guidance literature:

In acetonitrile; at 23 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/acs.orglett.8b00825

Reference yield: 99.0%

2,6-dichlorobenzeneethanimidamide (78622-21-6) + methyl 4,6-dimethyl-1,2,3-triazine-5-carboxylate → methyl 2-(2,6-dichlorobenzyl)-4,6-dimethylpyrimidine-5-carboxylate

Guidance literature:

In acetonitrile; at 60 ℃; for 24h;

DOI:10.1021/acs.joc.1c01553

upstream raw materials:

2,6-dichlorophenylacetonitrile

Downstream raw materials:

N-(N'-methylcarbamoyl)-2-(2,6-dichlorophenyl)acetamidine hydrochloride

4-[[4-amino-6-[(2,6-dichlorophenyl)methyl]-1,3,5-triazin-2-yl]-amino]benzonitrile

4-[2-(2,6-dichloro-benzyl)-3H-imidazol-4-yl]-piperidine-1-carboxylic acid tert-butyl ester

4-amino-N-[3-(2,6-dichloro-benzyl)-[1,2,4]thiadiazol-5-yl]-benzenesulfonamide