(+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone

Base Information

Chemical Name:(+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone
CAS No.:136410-41-8
Molecular Formula:C₁₉H₂₈FNO₂
Molecular Weight:321.435
Hs Code.:
DSSTox Substance ID:DTXSID80929427
Nikkaji Number:J423.562B

Synonyms:BRN 4757577;(+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone;2-Pyrrolidinone, 1-((3-fluorophenyl)methyl)-5-(octyloxy)-, (+-)-;136410-41-8;C19H28FNO2;SCHEMBL10649332;DTXSID80929427;LS-138825;5-(Octyloxy)-1-[3-fluorobenzyl]pyrrolidin-2-one;1-[(3-FLUOROPHENYL)METHYL]-5-(OCTYLOXY)PYRROLIDIN-2-ONE

Suppliers and Price of (+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone

Chemical Property:

Vapor Pressure:2.64E-08mmHg at 25°C
Boiling Point:450.4°C at 760 mmHg
Flash Point:226.2°C
Density:1.07g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:10
Exact Mass:321.21040730
Heavy Atom Count:23
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCOC1CCC(=O)N1CC2=CC(=CC=C2)F

Technology Process of (+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone

There total 2 articles about (+-)-1-((3-Fluorophenyl)methyl)-5-(octyloxy)-2-pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 119984-38-2
5-n-octyloxy-pyrrolidin-2-one

: 456-41-7
1-(Bromomethyl)-3-fluorobenzene

: 119984-52-0,136410-41-8
1-(3-Fluoro-benzyl)-5-octyloxy-pyrrolidin-2-one

Guidance literature:: With potassium hydroxide; tetrabutylammomium bromide; In tetrahydrofuran; for 2h; Ambient temperature;
DOI:10.1016/0223-5234(91)90102-S

Reference yield:

: 111-87-5
octanol

: 119984-52-0,136410-41-8
1-(3-Fluoro-benzyl)-5-octyloxy-pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 35 percent / Amberlite IR-120 (H⁺ form) / 4 h / 60 °C

2: 66 percent / KOH, tetrabutylammonium bromide / tetrahydrofuran / 2 h / Ambient temperature

With potassium hydroxide; Amberlite IR-120 (H⁺ form); tetrabutylammomium bromide; In tetrahydrofuran;
DOI:10.1016/0223-5234(91)90102-S