4-[4-(diphenylmethyl)piperazin-1-yl]-1-phenylbutan-1-one dihydrochloride

Base Information

• Chemical Name: 4-[4-(diphenylmethyl)piperazin-1-yl]-1-phenylbutan-1-one dihydrochloride
• CAS No.: 113913-48-7
• Molecular Formula: C₂₇H₃₀N₂O*2ClH
• Molecular Weight: 471.47
• Mol file: 113913-48-7.mol

Synonyms:1-Butanone,4-[4-(diphenylmethyl)-1-piperazinyl]-1-phenyl-, dihydrochloride (9CI)

Chemical Property of 4-[4-(diphenylmethyl)piperazin-1-yl]-1-phenylbutan-1-one dihydrochloride

Chemical Property:

• Vapor Pressure: 7.95E-12mmHg at 25°C
• Boiling Point: 542.4°Cat760mmHg
• Flash Point: 218.5°C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[4-(diphenylmethyl)piperazin-1-yl]-1-phenylbutan-1-one dihydrochloride

There total 2 articles about 4-[4-(diphenylmethyl)piperazin-1-yl]-1-phenylbutan-1-one dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

diphenylmethylpiperazine (841-77-0) + 4-chloro-1-phenylbutan-1-one (939-52-6) → 4-(4-Benzhydryl-piperazin-1-yl)-1-phenyl-butan-1-one; hydrochloride (113913-48-7)

Guidance literature:

With sodium hydrogencarbonate; In ethanol; for 24h; Heating;

Reference yield:

diphenylchloromethane (90-99-3) → 4-(4-Benzhydryl-piperazin-1-yl)-1-phenyl-butan-1-one; hydrochloride (113913-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / ethanol / 24 h / Heating

2: 33 percent / sodium bicarbonate / ethanol / 24 h / Heating

With sodium hydrogencarbonate; In ethanol;

upstream raw materials:

diphenylmethylpiperazine

4-chloro-1-phenylbutan-1-one

diphenylchloromethane

Refernces