Mabuterol hydrochloride

Base Information

Chemical Name:Mabuterol hydrochloride
CAS No.:54240-36-7
Molecular Formula:C₁₃H₁₈ClF₃N₂O*ClH
Molecular Weight:347.208
Hs Code.:29221990
European Community (EC) Number:632-649-6
UNII:536V290790
DSSTox Substance ID:DTXSID3046798
Wikidata:Q27261071
ChEMBL ID:CHEMBL3184272
Mol file:54240-36-7.mol

Synonyms:mabuterol hydrochloride;54240-36-7;Broncholin;Mabuterolhydrochloride;Mabuterol HCl;DTXSID3046798;1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;hydrochloride;PB-868;Mabuterol hydrochloride (JAN);Mabuterol hydrochloride [JAN];DTXCID1026798;1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert-butyl-D9-amino-ethanol hydrochloride;1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol hydrochloride;CAS-54240-36-7;UNII-536V290790;NCGC00181010-01;1-(4-amino-3-chloro-5-(trifluoromethyl)phenyl)-2-(tert-butylamino)ethanol hydrochloride;536V290790;Broncholin (TN);C13H18ClF3N2O.ClH;SCHEMBL123796;KF-868DS;PB-868CL;CHEMBL3184272;CHEBI:31791;DL-MABUTEROL HYDROCHLORIDE;MABUTEROL MONOHYDROCHLORIDE;Tox21_112660;KF-868;AKOS015888383;Tox21_112660_1;(+/-)-MABUTEROL HYDROCHLORIDE;C13-H18-Cl-F3-N2-O.Cl-H;MABUTEROL HYDROCHLORIDE [WHO-DD];NCGC00181010-02;FT-0769273;MABUTEROL DL-FORM HYDROCHLORIDE [MI];D01589;A870510;Q-201333;Q27261071;Mabuterol hydrochloride, VETRANAL(TM), analytical standard;1-(4'-Amino-3'-chloro-5'-trifluoromethyl-phenyl)-2-tert.butylamino-ethanol hydrochloride;1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethan-1-ol hydrochloride;95656-48-7;BENZENEMETHANOL, 4-AMINO-3-CHLORO-.ALPHA.-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-5-(TRIFLUOROMETHYL)-, HYDROCHLORIDE (1:1);BENZENEMETHANOL, 4-AMINO-3-CHLORO-.ALPHA.-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-5-(TRIFLUOROMETHYL)-, MONOHYDROCHLORIDE;Benzenemethanol, 4-amino-3-chloro-?-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-, monohydrochloride (9CI);KF 868;KF 868 (pharmaceutical);dl-Mabuterol hydrochloride;Benzenemethanol, 4-amino-3-chloro-?-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-, hydrochloride (1:1)

Suppliers and Price of Mabuterol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Mabuterol hydrochloride VETRANAL
10mg
$ 190.00

Crysdot
Mabuterol hydrochloride 95+%
1g
$ 668.00

Biosynth Carbosynth
Mabuterol hydrochloride
50 mg
$ 297.50

Biosynth Carbosynth
Mabuterol hydrochloride
10 mg
$ 85.00

American Custom Chemicals Corporation
MABUTEROL HYDROCHLORIDE 95.00%
5MG
$ 502.16

AK Scientific
Mabuterol hydrochloride
50mg
$ 451.00

Total 27 raw suppliers

Chemical Property of Mabuterol hydrochloride

Chemical Property:

Vapor Pressure:2.57E-06mmHg at 25°C
Melting Point:205-206 °C
Boiling Point:375.9°Cat760mmHg
Flash Point:181.1°C
PSA：58.28000
Density:g/cm³
LogP:5.13660
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:346.0826531
Heavy Atom Count:21
Complexity:320

Purity/Quality:

97% ^*data from raw suppliers

Mabuterol hydrochloride VETRANAL ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NCC(C1=CC(=C(C(=C1)Cl)N)C(F)(F)F)O.Cl
Description Mabuterol hydrochloride i s a β2-selective adrenergic agonist closely related to clenbuterol, and useful in the treatment of chronic bronchial asthma, bronchitis, and emphysema. Its oral potency and duration of action are reported to exceed those of salbutamol.
Uses Mabuterol Hydrochloride is an acidic salt of Mabuterol (M104000). Mabuterol is a β2-adrenergic agonist, used as a bronchodilator/antiasthmatic.

Technology Process of Mabuterol hydrochloride

There total 3 articles about Mabuterol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: