POLY-GAMMA-GLUTAMIC ACID

Base Information

• Chemical Name: POLY-GAMMA-GLUTAMIC ACID
• CAS No.: 84960-48-5
• Molecular Formula: C₅H₉NO₄
• Molecular Weight: 147.131
• Mol file: 84960-48-5.mol

Synonyms:L-Glutamic acid, homopolymer (9CI);alpha-L-Glutamic acid polymer;Poly(alpha-L-glutamic acid);

Chemical Property of POLY-GAMMA-GLUTAMIC ACID

Chemical Property:

• Boiling Point: 333.8oC at 760 mmHg
• Flash Point: 155.7oC
• PSA: 199.20000
• Density: 1.409 g/cm3
• LogP: -0.77850

Purity/Quality:

99%, ^*data from raw suppliers

POLY-GAMMA-GLUTAMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: Poly-gamma-glutamic acid (PGA) is a biopolymer with diverse applications in various fields. In the food industry, PGA serves as a natural food additive and stabilizer, used in products such as noodles, beverages, and dairy items, to enhance texture and prolong shelf life. In the pharmaceutical and medical fields, it has potential applications in drug delivery systems, tissue engineering, and wound healing due to its biocompatibility and biodegradability. In agriculture, PGA-based formulations can serve as eco-friendly crop protection agents, improving the efficacy of pesticides and reducing environmental impact. Additionally, in cosmetics and skincare, PGA is utilized in moisturizers and anti-aging products, contributing to skin hydration and elasticity. Its versatility as a biopolymer underscores its significance in food technology, pharmaceuticals, agriculture, and cosmetics, playing crucial roles in enhancing product quality and sustainability in these diverse fields.

Technology Process of POLY-GAMMA-GLUTAMIC ACID

There total 553 articles about POLY-GAMMA-GLUTAMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glutamic acid γ-p-nitroanilide (60133-17-7) → D-Glutamic acid (6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

With marine bivalve lysozyme; MOPS buffer; Tapes japonica; at 37 ℃; pH=7.0; Enzyme kinetics;

DOI:10.1007/s00018-003-3082-z

Reference yield:

α-ketoglutaric acid (328-50-7) + D-norvaline (2013-12-9,498-18-0) → D-Glutamic acid (6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + 2-oxopentanoic acid (1821-02-9)

Guidance literature:

With pyridoxal 5'-phosphate; recombinant Lactobacillus salivarius UCC₁₁₈ D-amino acid aminotransferase; In aq. phosphate buffer; at 30 ℃; for 0.0166667h; pH=7.5; Enzymatic reaction;

DOI:10.1016/j.molcatb.2013.04.013

Reference yield:

L-glutamic acid 5-(4-nitroanilide) (7300-59-6) → L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + 4-nitro-aniline (100-01-6,104810-17-5)

Guidance literature:

With marine bivalve lysozyme; MOPS buffer; Tapes japonica; at 37 ℃; pH=7.0; Enzyme kinetics;

DOI:10.1007/s00018-003-3082-z

upstream raw materials:

5-oxo-tetrahydro-furan-2-carboxylic acid

α-ketoglutaric acid

ethanol

methyl 2-benzamido-3-chloro-propanoate

Downstream raw materials:

(R)-αγ-Diaminobutyric acid

N-[(2,4-dichloro-phenoxy)-acetyl]-D-glutamic acid

N-benzylsulfanylcarbonyl-L-glutamic acid

N-(2-iodo-benzoyl)-L-glutamic acid

Refernces

• 1、 Wan, Xinhua,Wang, Zhaoxu,Ye, Xichong,Zhang, Jie. "Noncovalently Functionalized Commodity Polymers as Tailor-Made Additives for Stereoselective Crystallization". supporting information. p. 20243 - 20248. Retrieved 2021/08/09.
• 2、 Li, Tingting,Xu, Bo. "Mechanically Strong Heterogeneous Catalysts via Immobilization of Powderous Catalysts to Porous Plastic Tablets". supporting information. p. 2673 - 2678. Retrieved 2021/08/03.