2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide

Base Information

• Chemical Name: 2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide
• CAS No.: 5504-71-2
• Molecular Formula: C₁₅H₁₃ClN₂O₂
• Molecular Weight: 288.733
• DSSTox Substance ID: DTXSID50203589
• Nikkaji Number: J431.987G
• Wikidata: Q83076994
• ChEMBL ID: CHEMBL3277553
• Mol file: 5504-71-2.mol

Synonyms:2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide;5504-71-2;Acetamide, 2-amino-N-(2-benzoyl-4-chlorophenyl)-;2-AMINO-N-(2-BENZOYL-4-CHLOROPHENYL)ACETAMIDE HCL;CHEMBL3277553;DTXSID50203589;2-(Aminoacetylamino)-5-chlorobenzophenone;N-(2-benzoyl-4-chlorophenyl)-2-aminoacetamide

Chemical Property of 2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide

Chemical Property:

• Vapor Pressure: 5.83E-12mmHg at 25°C
• Boiling Point: 545.6°Cat760mmHg
• Flash Point: 283.8°C
• Density: 1.335g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 288.0665554
• Heavy Atom Count: 20
• Complexity: 356

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=C(C=CC(=C2)Cl)NC(=O)CN

Technology Process of 2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide

There total 2 articles about 2-Amino-N-(2-benzoyl-4-chlorophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<2-Benzoyl-4-chlor-phenyl-carbamoylmethyl>-carbaminsaeure-benzylester (29176-43-0) → 2-Amino-2'-benzoyl-4'-chloracetanilid (5504-71-2)

Guidance literature:

With hydrogen bromide; In acetic acid; for 1.5h; Ambient temperature;

DOI:10.1021/jm00133a006

Reference yield:

→ 2-Amino-2'-benzoyl-4'-chloracetanilid (5504-71-2)

Guidance literature:

2-Bromacetamino-5-chlor-benzophenon u. fl. NH3;

Reference yield: 64.0%

2-Amino-2'-benzoyl-4'-chloracetanilid (5504-71-2) + acetyl chloride (75-36-5) → 2--5-chlorobenzophenone (5497-11-0)

Guidance literature:

In N,N,N,N,N,N-hexamethylphosphoric triamide; for 3h; Ambient temperature;

DOI:10.1021/jm00133a006

upstream raw materials:

<2-Benzoyl-4-chlor-phenyl-carbamoylmethyl>-carbaminsaeure-benzylester

Downstream raw materials:

2--5-chlorobenzophenone