Phospho-L-arginine

Base Information

• Chemical Name: Phospho-L-arginine
• CAS No.: 1189-11-3
• Molecular Formula: C6H15 N4 O5 P
• Molecular Weight: 254.183
• Hs Code.: 2931900090
• European Community (EC) Number: 214-714-7
• DSSTox Substance ID: DTXSID10922805
• Nikkaji Number: J20.415C
• Wikidata: Q27103062
• Metabolomics Workbench ID: 51268
• Mol file: 1189-11-3.mol

Synonyms:arginine phosphate;phospho-L-arginine;phosphoarginine

Chemical Property of Phospho-L-arginine

Chemical Property:

• Vapor Pressure: 6.75E-13mmHg at 25°C
• Melting Point: >205°C (dec)
• Boiling Point: 562.2°Cat760mmHg
• Flash Point: 293.8°C
• PSA: 178.57000
• Density: 1.82g/cm³
• LogP: -0.03300
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Aqueous Acid (Slightly), Water (Slightly)
• XLogP3: -5.4
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 254.07800659
• Heavy Atom Count: 16
• Complexity: 314

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phospho-L-Arginine, Trisodium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(C(=O)O)N)CN=C(N)NP(=O)(O)O
• Isomeric SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)NP(=O)(O)O
• Uses: A hair growth stimulant A hair growth stimulant. Used in cosmetic composition.

Technology Process of Phospho-L-arginine

There total 6 articles about Phospho-L-arginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

L-arginine (74-79-3,25212-18-4) → N5-[imino(phosphonoamino)methyl]L-ornithine (1189-11-3)

Guidance literature:

With pyruvate kinase; arginine kinase; phosphoenolpyruvate; ATP; magnesium chloride; In water; for 48h; pH=8; Enzymatic reaction;

DOI:10.1002/cctc.201601080

Reference yield:

L-arginine (74-79-3,25212-18-4) → N5-[imino(phosphonoamino)methyl]L-ornithine (1189-11-3)

Guidance literature:

With arginine kinase; bei pH 9;

Reference yield:

L-ornithine (70-26-8,25104-12-5,410523-47-6) + N-Phosphoryl-ω-methyl-isoharnstoff (88916-81-8) → N5-[imino(phosphonoamino)methyl]L-ornithine (1189-11-3)

Guidance literature:

With hydroxide;

upstream raw materials:

L-ornithine

N-Phosphoryl-ω-methyl-isoharnstoff

L-arginine

Downstream raw materials:

L-arginine

phosphoric acid

Refernces

• 1、 Ruman, Tomasz,Dlugopolska, Karolina,Jurkiewicz, Agata,Rut, Dagmara,Fraczyk, Tomasz,Ciesla, Joanna,Les, Andrzej,Szewczuk, Zbigniew,Rode, Wojciech. "Thiophosphorylation of free amino acids and enzyme protein by thiophosphoramidate ions". experimental part. p. 74 - 80. Retrieved 2010/05/17.