L-ornithine

Base Information

• Chemical Name: L-ornithine
• CAS No.: 70-26-8
• Deprecated CAS: 7006-33-9,410523-46-5,204201-13-8
• Molecular Formula: C5H12N2O2
• Molecular Weight: 132.162
• Hs Code.: 2922499990
• European Community (EC) Number: 200-731-7
• NSC Number: 758894
• UNII: E524N2IXA3
• DSSTox Substance ID: DTXSID00883219
• Nikkaji Number: J9.177D
• Wikipedia: Ornithine
• Wikidata: Q410198
• NCI Thesaurus Code: C29611
• Pharos Ligand ID: X77237H6KSUJ
• Metabolomics Workbench ID: 37139
• ChEMBL ID: CHEMBL446143
• Mol file: 70-26-8.mol

Synonyms:2,5 Diaminopentanoic Acid;2,5-Diaminopentanoic Acid;Ornithine;Ornithine Dihydrochloride, (L)-Isomer;Ornithine Hydrochloride, (D)-Isomer;Ornithine Hydrochloride, (DL)-Isomer;Ornithine Hydrochloride, (L)-Isomer;Ornithine Monoacetate, (L)-Isomer;Ornithine Monohydrobromide, (L)-Isomer;Ornithine Monohydrochloride, (D)-Isomer;Ornithine Monohydrochloride, (DL)-Isomer;Ornithine Phosphate (1:1), (L)-Isomer;Ornithine Sulfate (1:1), (L)-Isomer;Ornithine, (D)-Isomer;Ornithine, (DL)-Isomer;Ornithine, (L)-Isomer

Chemical Property of L-ornithine

Chemical Property:

• Vapor Pressure: 1.08E-05mmHg at 25°C
• Melting Point: 140 °C
• Refractive Index: 1.4496 (estimate)
• Boiling Point: 308.718 °C at 760 mmHg
• PKA: 1.705(at 25℃)
• Flash Point: 140.508 °C
• PSA: 89.34000
• Density: 1.165 g/cm³
• LogP: 0.53780
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: -4.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 132.089877630
• Heavy Atom Count: 9
• Complexity: 95

Purity/Quality:

99.9% ^*data from raw suppliers

L-Ornithine 99 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,N
• Hazard Codes: T,N

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Amino Acids and Derivatives
• Canonical SMILES: C(CC(C(=O)O)N)CN
• Isomeric SMILES: C(C[C@@H](C(=O)O)N)CN
• Recent NIPH Clinical Trials: Effect of intake of supplements containing ornithine on human health.
• Uses: Biochemical research; medicine. hepatoprotectant, anticholesteremic

Technology Process of L-ornithine

There total 128 articles about L-ornithine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17(13)C4H18(2)H3N(15)N2O3 → 2,5-diaminopentanoic acid (70-26-8,348-66-3,616-07-9,7006-33-9,25104-12-5,410523-47-6)

Guidance literature:

C₁₇⁽¹³⁾C₄H₁₈⁽²⁾H₃N⁽¹⁵⁾N₂O₃; With palladium diacetate; In methanol; chloroform; at 0 ℃; for 0.0833333h;

at 0 ℃; for 0.666667h; Aqueous phophate buffer;

With hydrogenchloride; In water; at 140 ℃; for 5h;

Reference yield:

ethyl 2-acetamido-4-cyano-2-ethoxycarbonylbutanoate (5440-42-6) → 2,5-diaminopentanoic acid (70-26-8,348-66-3,616-07-9,7006-33-9,25104-12-5,410523-47-6)

Guidance literature:

With methanol; nickel; at 70 - 100 ℃; under 51485.6 - 58840.6 Torr; Hydrogenation_.Erhitzen des jeweils erhaltenen Reaktionsprodukts mit wss. HCl;

Reference yield:

→ 2,5-diaminopentanoic acid (70-26-8,348-66-3,616-07-9,7006-33-9,25104-12-5,410523-47-6)

Guidance literature:

With methanol; nickel; at 70 - 100 ℃; under 51485.6 - 58840.6 Torr; Hydrogenation_.Erhitzen des jeweils erhaltenen Reaktionsprodukts mit wss. HCl;

upstream raw materials:

3-aminopiperidin-2-one

D-ornithine

(R,S)-2-aminoadipic acid

D-arginine

Downstream raw materials:

3-hydroxytetrahydro-2H-pyran-2-one

5-amino-2-oxo-valeric acid

1,4-diaminobutane

L-arginine

Refernces

• 1、 Bian, Xiaoying,Dai, Guangzhi,Jiao, Nianzhi,Liu, Yang,Ravichandran, Vinothkannan,Ren, Xiangmei,Shen, Qiyao,Sui, Haiyan,Zhang, Youming,Zhong, Lin,Zhou, Haibo. "Saccharochelins A-H, Cytotoxic Amphiphilic Siderophores from the Rare Marine Actinomycete Saccharothrix sp. D09". . p. 2149 - 2156. Retrieved 2021/08/20.
• 2、 Chen, Ziming,Huang, Hongbo,Ju, Jianhua,Luo, Minghe,Song, Xiaoxian,Wang, Xin,Zang, Ruochen. "Natural Hydroxamate-Containing Siderophore Acremonpeptides A-D and an Aluminum Complex of Acremonpeptide D from the Marine-Derived Acremonium persicinum SCSIO 115". . p. 2594 - 2600. Retrieved 2019/10/11.