2-Chloro-2,2-diphenylacetyl chloride

Base Information

• Chemical Name: 2-Chloro-2,2-diphenylacetyl chloride
• CAS No.: 2902-98-9
• Molecular Formula: C14H10Cl2O
• Molecular Weight: 265.139
• Hs Code.: 29163900
• European Community (EC) Number: 220-798-6
• NSC Number: 400463
• UNII: WDU827PD7T
• DSSTox Substance ID: DTXSID00183261
• Nikkaji Number: J55.071J
• Wikidata: Q72449709
• Mol file: 2902-98-9.mol

Synonyms:2-Chloro-2,2-diphenylacetyl chloride;2902-98-9;Chlorodiphenylacetyl chloride;ACETYL CHLORIDE, CHLORODIPHENYL-;benzeneacetyl chloride, alpha-chloro-alpha-phenyl-;Diphenylchloroacetylchloride;alpha-Chloro-alpha,alpha-diphenylacetyl chloride;alpha-Chloro-alpha-phenylbenzeneacetyl chloride;EINECS 220-798-6;NSC 400463;diphenylchloroacetyl chloride;BRN 0981727;AI3-16120;chloro(diphenyl)acetyl chloride;NSC-400463;3-09-00-03308 (Beilstein Handbook Reference);Benzeneacetyl chloride, .alpha.-chloro-.alpha.-phenyl-;Diphenylchloroacetylchlorid;WDU827PD7T;SCHEMBL1321231;C14-H10-Cl2-O;Diphenylchloroacetic acid chloride;DTXSID00183261;alpha-Chlorodiphenylacetyl chloride;diphenyl-alpha-chloroacetyl chloride;NSC400463;AKOS000121269;2-chloro-2,2-diphenyl-acetyl chloride;2-Chloro-2,2-diphenylacetyl chloride, 97%;FT-0611692;A819724;4-(3-Cyanobenzyloxy)-5-methoxy-2-nitrobenzaldehyde;J-017360;.alpha.-Chloro-.alpha.,.alpha.-diphenylacetyl chloride

Chemical Property of 2-Chloro-2,2-diphenylacetyl chloride

Chemical Property:

• Appearance/Colour: white to light yellow crystalline solid
• Vapor Pressure: 0.000562mmHg at 25°C
• Melting Point: 48-50 °C(lit.)
• Refractive Index: 1.589
• Boiling Point: 311.5 °C at 760 mmHg
• Flash Point: 140.8 °C
• PSA: 17.07000
• Density: 1.286 g/cm³
• LogP: 3.93440
• Storage Temp.: 0-6°C
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 264.0108703
• Heavy Atom Count: 17
• Complexity: 247

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-2,2-diphenylacetyl chloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34-36/37
• Safety Statements: 26-27-28-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)Cl)Cl

Technology Process of 2-Chloro-2,2-diphenylacetyl chloride

There total 16 articles about 2-Chloro-2,2-diphenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

diphenyl ketene (525-06-4) → 2-chloro-2,2-diphenylacetyl chloride (2902-98-9)

Guidance literature:

With phosphorus pentachloride; In dichloromethane; for 10h; Heating;

Reference yield:

benzophenone (119-61-9) → Dichlorodiphenylmethane (2051-90-3) + 2-chloro-2,2-diphenylacetyl chloride (2902-98-9)

Guidance literature:

With phenyl(bromodichloromethyl)mercury; dimethyl acetylenedicarboxylate; In benzene; at 80 ℃; for 19h; Product distribution;

DOI:10.1021/jo00159a022

Reference yield:

Benzilic acid (76-93-7) → 2-chloro-2,2-diphenylacetyl chloride (2902-98-9)

Guidance literature:

With phosphorus pentachloride;

DOI:10.1039/jr9470000164

upstream raw materials:

diphenyl ketene

Benzilic acid

phosgene

diazodiphenylmethane

Downstream raw materials:

4-(chloro-diphenyl-acetyl)-morpholine

1-(chloro-diphenyl-acetyl)-4-methyl-piperazine

1-methyl-4-[(4-methyl-piperazino)-diphenyl-acetyl]-piperazine

1-(hydroxy-diphenyl-acetyl)-4-ethyl-piperazine