p-ARSANILIC ACID, 2-HYDROXY-

Base Information

• Chemical Name: p-ARSANILIC ACID, 2-HYDROXY-
• CAS No.: 6318-57-6
• Molecular Formula: C₆H₈AsNO₄
• Molecular Weight: 233.055
• European Community (EC) Number: 663-988-8
• NSC Number: 31664
• UNII: Q7EH634AU9
• DSSTox Substance ID: DTXSID10212531
• Nikkaji Number: J33.867B
• Wikidata: Q83087679
• ChEMBL ID: CHEMBL1984386
• Mol file: 6318-57-6.mol

Synonyms:p-ARSANILIC ACID, 2-HYDROXY-;6318-57-6;4-Amino-2-hydroxybenzenearsonic acid;(4-AMINO-2-HYDROXYPHENYL)ARSONIC ACID;Benzenearsonic acid, 4-amino-2-hydroxy-;Arsonic acid, (4-amino-2-hydroxyphenyl)-;NSC 31664;BRN 3270180;MLS000737632;Q7EH634AU9;NSC-31664;3-16-00-01135 (Beilstein Handbook Reference);2-Hydroxyarsanilic acid;UNII-Q7EH634AU9;WLN: ZR CQ D-AS-QQO;C6-H8-As-N-O4;SCHEMBL6676509;CHEMBL1984386;DTXSID10212531;NSC31664;(4-amino-2-hydroxy-phenyl)arsonic acid;4-Amino-2-(hydroxybenzene)arsonic acid;LS-21707;NCI60_002722;SMR000393802;AS-(4-AMINO-2-HYDROXYPHENYL)ARSONIC ACID;ARSONIC ACID, AS-(4-AMINO-2-HYDROXYPHENYL)-

Chemical Property of p-ARSANILIC ACID, 2-HYDROXY-

Chemical Property:

• Vapor Pressure: 8.05E-15mmHg at 25°C
• Boiling Point: 591.2°Cat760mmHg
• Flash Point: 311.3°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 232.966927
• Heavy Atom Count: 12
• Complexity: 204

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1N)O)[As](=O)(O)O

Technology Process of p-ARSANILIC ACID, 2-HYDROXY-

There total 3 articles about p-ARSANILIC ACID, 2-HYDROXY- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-ethoxycarbonylamino-2-hydroxy-phenyl)-arsonic acid (6266-19-9) → (4-amino-2-hydroxy-phenyl)-arsonic acid (6318-57-6)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01868a067

Reference yield:

(2-hydroxy-4-nitro-phenyl)-arsonic acid (860517-85-7) → (4-amino-2-hydroxy-phenyl)-arsonic acid (6318-57-6)

Guidance literature:

With iron; acetic acid;

Reference yield:

ethyl N-(3-hydroxyphenyl)carbamate (7159-96-8) → (4-amino-2-hydroxy-phenyl)-arsonic acid (6318-57-6)

Guidance literature:

Multi-step reaction with 2 steps

2: aqueous NaOH-solution

With sodium hydroxide;

DOI:10.1021/ja01868a067

upstream raw materials:

(4-ethoxycarbonylamino-2-hydroxy-phenyl)-arsonic acid

(2-hydroxy-4-nitro-phenyl)-arsonic acid

ethyl N-(3-hydroxyphenyl)carbamate

Downstream raw materials:

(2,2'-dihydroxy-4,4'-ureylene-diphenyl)-bis-arsonic acid

[2-hydroxy-4-(3-nitro-benzoylamino)-phenyl]-arsonic acid

[2-hydroxy-5-nitro-4-(3-nitro-benzoylamino)-phenyl]-arsonic acid

(4-amino-2-hydroxy-5-nitro-phenyl)-arsonic acid