Antineoplastic-32873

Base Information

• Chemical Name: Antineoplastic-32873
• CAS No.: 6266-19-9
• Molecular Formula: C₉H₁₂AsNO₆
• Molecular Weight: 305.119
• European Community (EC) Number: 684-718-5
• NSC Number: 32873
• DSSTox Substance ID: DTXSID80978233
• Wikidata: Q82963566
• ChEMBL ID: CHEMBL1363604
• Mol file: 6266-19-9.mol

Synonyms:6266-19-9;MLS000737653;ANTINEOPLASTIC-32873;NSC32873;CHEMBL1363604;DTXSID80978233;HMS2748O11;NSC-32873;SMR000393822;(4-{[Ethoxy(hydroxy)methylidene]amino}-2-hydroxyphenyl)arsonic acid

Chemical Property of Antineoplastic-32873

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 304.988057
• Heavy Atom Count: 17
• Complexity: 317

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NC1=CC(=C(C=C1)[As](=O)(O)O)O

Technology Process of Antineoplastic-32873

There total 2 articles about Antineoplastic-32873 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

orthoarsenic acid (7778-39-4,121471-47-4,1327-52-2) + ethyl N-(3-hydroxyphenyl)carbamate (7159-96-8) → (4-ethoxycarbonylamino-2-hydroxy-phenyl)-arsonic acid (6266-19-9)

Guidance literature:

DOI:10.1021/ja01868a067

Reference yield:

(4-amino-2-hydroxy-phenyl)-arsonic acid (6318-57-6) + chloroformic acid ethyl ester (541-41-3) → (4-ethoxycarbonylamino-2-hydroxy-phenyl)-arsonic acid (6266-19-9)

Guidance literature:

With alkali;

Reference yield:

(4-ethoxycarbonylamino-2-hydroxy-phenyl)-arsonic acid (6266-19-9) → (4-amino-2-hydroxy-phenyl)-arsonic acid (6318-57-6)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01868a067

upstream raw materials:

(4-amino-2-hydroxy-phenyl)-arsonic acid

chloroformic acid ethyl ester

orthoarsenic acid

ethyl N-(3-hydroxyphenyl)carbamate

Downstream raw materials:

(4-amino-2-hydroxy-phenyl)-arsonic acid

(4-ethoxycarbonylamino-2-methoxy-phenyl)-arsonic acid